| Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
| Curcumin | 📋 | ✍ | ⛔ | | 38634264 | Curcumin Effects on Age-Related Changes in Oral Immunity: An In Vivo Study |
| Vitamin D3 | 📋 | ✍ | ⛔ | | 38629361 | Effects of Vitamin D and E Supplementation on Prevention of Bronchopulmonary Dysplasia (BPD) in Premature Neonates: A Systematic Review and Meta-Analysis |
| Ginsenosides | 📋 | ✍ | ⛔ | | 38671369 | Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer |
| Resveratrol | 📋 | ✍ | ⛔ | | 38710061 | Protective Effects of Resveratrol Against Airway Hyperreactivity, Oxidative Stress, and Lung Inflammation in a Rat Pup Model of Bronchopulmonary Dysplasia |
| Vitamin C | 📋 | ✍ | ⛔ | | 38518722 | Exploring the impact of high-altitude de-acclimatization on renal function: The roles of oxidative and endoplasmic reticulum stress in rat models |
| Quercetin | 📋 | ✍ | ⛔ | | 38556603 | Quercetin prophylaxis protects the kidneys by modulating the renin-angiotensin-aldosterone axis under acute hypobaric hypoxic stress |
| Melatonin | 📋 | ✍ | ⛔ | | 38688425 | Melatonin prevents pulmonary fibrosis caused by PM2.5 exposure by targeting epithelial-mesenchymal transition |
| EGCG | 📋 | ✍ | ⛔ | | 38662666 | Epigallocatechin gallate regulates the myeloid-specific transcription factor PU.1 in macrophages |
| N-Acetyl Cysteine | 📋 | ✍ | ⛔ | | 38555190 | N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis/Pre-COPD: Distinct Meta-analyses |
| Salidroside | 📋 | | | | 38727159 | Salidroside Ameliorates Lung Injury Induced by PM 2.5by Regulating SIRT1-PGC-1α in Mice |
| Astragalosides | 📋 | ✍ | ⛔ | | 38514749 | Astragaloside IV restrains pulmonary fibrosis progression via the circ_0008898/miR-211-5p/HMGB1 axis |
| Berberine | 📋 | ✍ | ⛔ | | 38729536 | Coptidis rhizoma extract alleviates oropharyngeal candidiasis by gC1qR-EGFR/ERK/c-fos axis-induced endocytosis of oral epithelial cells |
| Metformin | 📋 | ✍ | ⛔ | | 38479708 | Metformin and buparlisib synergistically induce apoptosis of non-small lung cancer (NSCLC) cells via Akt/FoxO3a/Puma axis |
| Luteolin | 📋 | ✍ | ⛔ | | 38646808 | Luteolin Inhibits Lung Cancer Cell Migration by Negatively Regulating TWIST1 and MMP2 Through Upregulation of miR-106a-5p |
| Ginseng | 📋 | ✍ | ⛔ | | 38632037 | Panax notoginseng saponins improve oral submucous fibrosis by inhabiting the Wnt/β-catenin signal pathway |
| Zinc | 📋 | ✍ | ⛔ | | 38348004 | Investigating the Efficacy of Zinc and Vitamin A in Treating Pediatric Community-Acquired Pneumonia |
| Echinacea | 📋 | ✍ | ⛔ | | 38667040 | Echinacea Reduces Antibiotics by Preventing Respiratory Infections: A Meta-Analysis (ERA-PRIMA) |
| Vitamin E | 📋 | ✍ | ⛔ | | 38125893 | Vitamin E stabilizes iron and mitochondrial metabolism in pulmonary fibrosis |
| Sulforaphane | 📋 | ✍ | ⛔ | | 38547510 | Sulforaphane improves redox homeostasis and right ventricular contractility in a model of pulmonary hypertension |
| Andrographolide | 📋 | | | | 37957849 | Andrographolide Attenuates RSV-induced Inflammation by Suppressing Apoptosis and Promoting Pyroptosis after Respiratory Syncytial Virus Infection In Vitro |
| Fucoidan | 📋 | ✍ | ⛔ | | 37780215 | Antimetastatic effect of fucoidan against non-small cell lung cancer by suppressing non-receptor tyrosine kinase and extracellular signal-related kinase pathway |
| Baicalin | 📋 | ✍ | ⛔ | | 38628726 | Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis |
| Bee Propolis | 📋 | ✍ | ⛔ | | 38729541 | Prophylactic use of standardized extract of propolis of Apis mellifera (EPP-AF®) reduces lung inflammation and improves survival in experimental lethal sepsis |
| Cannabidiol | 📋 | ✍ | ⛔ | | 38558822 | Discovering single cannabidiol or synergistic antitumor effects of cannabidiol and cytokine-induced killer cells on non-small cell lung cancer cells |
| Fisetin | 📋 | ✍ | ⛔ | | 35886884 | Increase in Anticancer Drug-Induced Toxicity by Fisetin in Lung Adenocarcinoma A549 Spheroid Cells Mediated by the Reduction of Claudin-2 Expression |
| Baicalein | 📋 | ✍ | ⛔ | | 38664950 | Baicalein exerts beneficial effects in lipopolysaccharide-induced pulmonary inflammation by modulating macrophage polarization and inhibiting pyroptosis |
| Astaxanthin | 📋 | ✍ | ⛔ | | 38649975 | Astaxanthin suppresses the malignant behaviors of nasopharyngeal carcinoma cells by blocking PI3K/AKT and NF-κB pathways via miR-29a-3p |
| Emodin | 📋 | | ⛔ | | 38540100 | The Application of Emodin Treatment on Nasopharyngeal Carcinoma Therapy |
| Apigenin | 📋 | ✍ | ⛔ | | 37707699 | Idiopathic pulmonary fibrosis (IPF): disease pathophysiology, targets, and potential therapeutic interventions |
| Tanshinone | 📋 | | | | 38697470 | Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-13C5]-glutamine metabolic flux analysis |
| Pterostilbene | 📋 | ✍ | ⛔ | | 38583346 | Insights into the mechanism of action of pterostilbene against influenza A virus-induced acute lung injury |
| Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 38687147 | Higher Plasma Omega-3 Levels are Associated With Improved Exacerbation Risk and Respiratory-Specific Quality of Life in COPD |
| Licorice Root | 📋 | ✍ | ⛔ | | 37958031 | The Power of Licorice ( Radix glycyrrhizae) to Improve Oral Health: A Comprehensive Review of Its Pharmacological Properties and Clinical Implications |
| Nigella Sativa | 📋 | ✍ | ⛔ | | 37621284 | Nigella sativa oil mitigates xerostomia and preserves salivary function in radiotherapy-treated mice |
| Lycopene | 📋 | ✍ | ⛔ | | 36167720 | Efficacy of lycopene for management of oral potentially malignant disorders: A systematic review and meta-analysis |
| Docosahexaenoic Acid | 📋 | ✍ | ⛔ | | 38613004 | Impact of 1-Year Supplementation with High-Rich Docosahexaenoic Acid (DHA) on Clinical Variables and Inflammatory Biomarkers in Pediatric Cystic Fibrosis: A Randomized Double-Blind Controlled Trial |
| Genistein | 📋 | ✍ | ⛔ | | 37817434 | Genistein alleviates pulmonary fibrosis by inactivating lung fibroblasts |
| Grape Seed extract | 📋 | ✍ | ⛔ | | 37566293 | Grape Seed Proanthocyanidin Ameliorates LPS-induced Acute Lung Injury By Modulating M2a Macrophage Polarization Via the TREM2/PI3K/Akt Pathway |
| Hesperidin | 📋 | ✍ | ⛔ | | 38435153 | Hesperidin Inhibits Oral Cancer Cell Growth via Apoptosis and Inflammatory Signaling-Mediated Mechanisms: Evidence From In Vitro and In Silico Analyses |
| Puerarin | 📋 | ✍ | ⛔ | | 38598838 | UNVEILING THE PROTECTIVE MECHANISMS OF PUERARIN AGAINST ACUTE LUNG INJURY: A COMPREHENSIVE EXPLORATION OF THE ROLES AND MECHANISMS OF MST1/ERS SIGNALING |
| Licochalcones | 📋 | | | | 37859622 | Licochalcone A induces cell cycle arrest and apoptosis via suppressing MAPK signaling pathway and the expression of FBXO5 in lung squamous cell cancer |
| Naringenin | 📋 | ✍ | ⛔ | | 38322119 | Promotion of ROS-mediated apoptosis, G2/M arrest, and autophagy by naringenin in non-small cell lung cancer |
| Honey | 📋 | ✍ | ⛔ | | 38710295 | Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials |
| Kaempferol | 📋 | ✍ | ⛔ | | 38681737 | Protective effect of kaempferol glucoside against lipopolysaccharide-caused acute lung injury via targeting Nrf2/NF-κB/NLRP3/GSDMD: Integrating experimental and computational studies |
| Vitamin A | 📋 | ✍ | ⛔ | | 38348004 | Investigating the Efficacy of Zinc and Vitamin A in Treating Pediatric Community-Acquired Pneumonia |
| Astragalus Root | 📋 | ✍ | ⛔ | | 38584671 | Ferroptosis Mediates Pulmonary Fibrosis: Implications for the Effect of Astragalus and Panax notoginseng Decoction |
| Hesperetin | 📋 | | | | 36196892 | Hesperetin induces apoptosis in A549 cells via the Hsp70‑mediated activation of Bax |
| Medicinal Plants | 📋 | | | | 37901462 | Proposed mechanisms of action of herbal drugs and their biologically active constituents in the treatment of coughs: an overview |
| Glycyrrhizic Acid | 📋 | ✍ | ⛔ | | 36423713 | Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome in vitro and in vivo |
| Magnesium | 📋 | ✍ | ⛔ | | 38395640 | Intravenous magnesium sulfate for asthma exacerbations in children: Systematic review with meta-analysis |
| Micronutrients | 📋 | | ⛔ | | 38613061 | Improvement of Lung Function by Micronutrient Supplementation in Patients with COPD: A Systematic Review and Meta-Analysis |
| Phytochemicals | 📋 | | | | 38611874 | Advances in Small Molecular Agents against Oral Cancer |
| Reishi Mushrooms | 📋 | ✍ | ⛔ | | 37745066 | The medicinal mushroom Ganoderma lucidum prevents lung tumorigenesis induced by tobacco smoke carcinogens |
| L-Arginine | 📋 | ✍ | ⛔ | | 38493696 | L-arginine mitigates bleomycin-induced pulmonary fibrosis in rats through regulation of HO-1/PPAR-γ/β-catenin axis |
| Probiotics | 📋 | ✍ | ⛔ | | 38352209 | The impact of probiotics and vitamin C on the prevention of upper respiratory tract symptoms in two preschool children cohorts |
| Selenium | 📋 | ✍ | ⛔ | | 37994159 | Selenium enhances photodynamic therapy of C-phycocyanin against lung cancer via dual regulation of cytotoxicity and antioxidant activity |
| Silibinin | 📋 | ✍ | | | 38484626 | Silibinin is a suppressor of the metastasis-promoting transcription factor ID3 |
| Chrysin | 📋 | ✍ | ⛔ | | 38675475 | Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer |
| Crocin | 📋 | ✍ | ⛔ | | 37424236 | Crocin Inhibits the Type 2 Inflammatory Response Produced by ILC2s in Eosinophilic Nasal Polyps |
| Thymoquinone | 📋 | | ⛔ | | 38518935 | Structure-based investigation of pyruvate dehydrogenase kinase-3 inhibitory potential of thymoquinone, targeting lung cancer therapy |
| Dihydroartemisinin | 📋 | | | | 38678671 | Dihydroartemisinin inhibits tumor progress via blocking ROR1-induced STAT3-activation in non-small cell lung cancer |
| Gingerol | 📋 | ✍ | | | 38181675 | 6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway |
| Capsaicin | 📋 | ✍ | ⛔ | | 38449809 | Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition |
| Ginkgo Biloba | 📋 | ✍ | ⛔ | | 38428907 | Exploration of Ginkgo biloba leaves on non-small cell lung cancer based on network pharmacology and molecular docking |
| Green Tea Polyphenols | 📋 | ✍ | ⛔ | | 38605739 | Green Tea Extract Reduced Lipopolysaccharide-Induced Inflammation in L2 Cells as Acute Respiratory Distress Syndrome Model Through Genes and Cytokine Pro-Inflammatory |
| Nobiletin | 📋 | ✍ | | | 38522319 | Recent advances in the therapeutic potential of nobiletin against respiratory diseases |
| Salvianolic Acid | 📋 | | | | 37953063 | Salvianolic acid B protects against pulmonary fibrosis by attenuating stimulating protein 1-mediated macrophage and alveolar type 2 cell senescence |
| Aloe Vera | 📋 | ✍ | ⛔ | | 37694023 | Assessment of Aloe Vera and Tulsi's Effectiveness in Treating Oral Submucous Fibrosis |
| Caffeine | 📋 | ✍ | ⛔ | | 37889643 | Cardiorespiratory and Neuroprotective Effects of Caffeine in Neonate Animal Models |
| Ellagic Acid | 📋 | ✍ | ⛔ | | 36901532 | Ellagic Acid Prevents Particulate Matter-Induced Pulmonary Inflammation and Hyperactivity in Mice: A Pilot Study |
| Icariin | 📋 | ✍ | | | 38467082 | Icariin ameliorates LPS-induced acute lung injury in mice via complement C5a-C5aR1 and TLR4 signaling pathways |
| L-Glutamine | 📋 | ✍ | ⛔ | | 38493953 | Clinical and biochemical assessment of the effect of glutamine in management of radiation induced oral mucositis in patients with head and neck cancer: Randomized controlled clinical trial |
| Pomegranate | 📋 | | ⛔ | | 36547050 | Application of the Extracts of Punica granatum in Oral Cancer: Scoping Review |
| Schisandrins | 📋 | | | | 38376003 | Schizandrin A induces non-small cell lung cancer apoptosis by suppressing the epidermal growth factor receptor activation |
| Allicin | 📋 | ✍ | ⛔ | | 37700925 | Anti Inflammatory Action of Allium Sativum Ethanol Extract to Prevent Lung Damage in Smoker Rat Model |
| Arctigenin | 📋 | | | | 36852795 | Effects of Arctigenin in Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma 5-8F Cells |
| Asiatic Acid | 📋 | | | | 37375849 | Asiatic Acid Inhibits Nasopharyngeal Carcinoma Cell Viability and Migration via Suppressing STAT3 and Claudin-1 |
| Carvacrol | 📋 | ✍ | ⛔ | | 38605312 | The inhibitory effects of carvacrol, nystatin, and their combination on oral candidiasis isolates |
| Dihydromyricetin | 📋 | ✍ | ⛔ | | 36807944 | Dihydromyricetin suppresses tumor growth via downregulation of the EGFR/Akt/survivin signaling pathway |
| Fucoxanthin | 📋 | ✍ | ⛔ | | 37313537 | Bixin and Fuxoxanthin Alone and in Combination with Cisplatin Regulate ABCC1 and ABCC2 Transcription in A549 Lung Cancer Cells |
| Gallic Acid | 📋 | | ⛔ | | 38275661 | Gallic Acid Protects from Sepsis-Induced Acute Lung Injury |
| Ginkgolides | 📋 | | | | 35952968 | Metabolomics and integrated network pharmacology analysis reveal that ginkgolides act as potential active anticancer components by regulating one-carbon metabolism |
| Green Tea | 📋 | ✍ | ⛔ | | 36647481 | Preventive and therapeutic effects of green tea on lung cancer: a narrative review of evidence from clinical and basic research |
| Mangiferin | 📋 | | ⛔ | | 38225395 | Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis |
| Myricetin | 📋 | | ⛔ | | 38015259 | The mechanism of action of myricetin against lung adenocarcinoma based on bioinformatics, in silico and in vitro experiments |
| Pine Bark | 📋 | ✍ | ⛔ | | 38465002 | The effects of Pycnogenol, a pine bark extract on pulmonary inflammation by Asian sand dust in mice |
| Turmeric | 📋 | ✍ | ⛔ | | 38560351 | Efficacy of turmeric in the treatment of oral mucositis in patients with head and neck cancer after radiotherapy or chemoradiotherapy: a systematic review and meta-analysis |
| Wogonin | 📋 | ✍ | ⛔ | | 36661523 | Deciphering the Mechanism of Wogonin, a Natural Flavonoid, on the Proliferation of Pulmonary Arterial Smooth Muscle Cells by Integrating Network Pharmacology and In Vitro Validation |
| Cinnamaldehyde | 📋 | | | | 36340192 | Cinnamaldehyde regulates mitochondrial quality against hydrogen peroxide induced apoptosis in mouse lung mesenchymal stem cells via the PINK1/Parkin signaling pathway |
| CoQ10 | 📋 | ✍ | ⛔ | | 38307422 | Effect of ubiquinol on electrophysiology during high-altitude acclimatization and de-acclimatization: A substudy of the Shigatse CARdiorespiratory fitness (SCARF) randomized clinical trial |
| Cordyceps | 📋 | ✍ | ⛔ | | 38528546 | Cordyceps sinensis relieves non-small cell lung cancer by inhibiting the MAPK pathway |
| Holy Basil | 📋 | ✍ | ⛔ | | 37694023 | Assessment of Aloe Vera and Tulsi's Effectiveness in Treating Oral Submucous Fibrosis |
| Schisandra | 📋 | ✍ | ⛔ | | 35416657 | Chemical Characterization and Potential Mechanism of the Anti-Asthmatic Activity of a Subfraction from Schisandra chinensis Fruit Extract |
| Ginger | 📋 | ✍ | ⛔ | | 37342461 | Treatment of the common cold with herbs used in Ayurveda and Jamu: monograph review and the science of ginger, liquorice, turmeric and peppermint |
| Skullcap | 📋 | ✍ | ⛔ | | 38723528 | Scutellaria baicalensis water decoction ameliorates lower respiratory tract infection by modulating respiratory microbiota |
| TUDCA | 📋 | ✍ | ⛔ | | 38518722 | Exploring the impact of high-altitude de-acclimatization on renal function: The roles of oxidative and endoplasmic reticulum stress in rat models |
| Andrographis | 📋 | ✍ | ⛔ | | 37821383 | Efficacy of Andrographis paniculata spray in acute pharyngitis: A randomized controlled trial |
| Artemisinin | 📋 | | | | 37699886 | Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development |
| Dihydroquercetin | 📋 | | | | 37835514 | Taxifolin Inhibits the Growth of Non-Small-Cell Lung Cancer via Downregulating Genes Displaying Novel and Robust Associations with Immune Evasion Factors |
| Galangin | 📋 | | | | 34931454 | Galangin as a direct inhibitor of vWbp protects mice from Staphylococcus aureus-induced pneumonia |
| Garlic | 📋 | ✍ | ⛔ | | 37836382 | Antioxidant and Antiproliferative Activities of Several Garlic Forms |
| Piperine | 📋 | ✍ | ⛔ | | 37762259 | Piperine Induces Apoptosis and Autophagy in HSC-3 Human Oral Cancer Cells by Regulating PI3K Signaling Pathway |
| Red Sage | 📋 | ✍ | ⛔ | | 38701934 | Salvia miltiorrhiza inhibited lung cancer through aerobic glycolysis suppression |
| Rhodiola | 📋 | ✍ | ⛔ | | 38503156 | Rhodiola crenulata alleviates hypobaric hypoxia-induced brain injury by maintaining BBB integrity and balancing energy metabolism dysfunction |
| Thyme | 📋 | ✍ | ⛔ | | 38186189 | Thymus vulgaris ameliorates cough in children with asthma exacerbation: a randomized, triple-blind, placebo-controlled clinical trial |
| Asiaticoside | 📋 | | | | 38664244 | Asiaticoside alleviates lipopolysaccharide-induced acute lung injury by blocking Sema4D/CD72 and inhibiting mitochondrial dysfunction in RAW264.7 cell and mice |
| Cinnamon | 📋 | ✍ | ⛔ | | 36034804 | Cinnamomum cassia (L.) J.Presl Alleviates Allergic Responses in Asthmatic Mice via Suppression of MAPKs and MMP-9 |
| Essential Oils | 📋 | | ⛔ | | 36529244 | Pharmacologic effects approach of essential oils and their components on respiratory diseases |
| Lipoic Acid | 📋 | ✍ | ⛔ | | 34746462 | Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in rats |
| Polydatin | 📋 | ✍ | | | 38025835 | Polydatin alleviates sepsis‑induced acute lung injury via downregulation of Spi‑B |
| Rosmarinic Acid | 📋 | ✍ | | | 38417242 | Alleviation of allergic asthma by rosmarinic acid via gut-lung axis |
| Ashwagandha | 📋 | ✍ | ⛔ | | 38303989 | In vitro cytotoxicity of Withania somnifera (L.) roots and fruits on oral squamous cell carcinoma cell lines: a study supported by flow cytometry, spectral, and computational investigations |
| Balloon Flower | 📋 | ✍ | ⛔ | | 38433216 | Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitis |
| Bromelain | 📋 | ✍ | ⛔ | | 37109265 | A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study |
| Butyrate | 📋 | | ⛔ | | 38560222 | Butyrate attenuates the stemness of lung cancer cells through lysosome Fe2+- and SLC7A11-mediated ferroptosis |
| Chamomile | 📋 | ✍ | ⛔ | | 38710295 | Efficacy of Natural Products in Preventing Oral Mucositis Resulting from Cancer Therapies: A Network Meta-analysis of Randomized Controlled Trials |
| Chlorogenic Acid | 📋 | ✍ | ⛔ | | 38356488 | Chlorogenic Acid Inhibits Progressive Pulmonary Fibrosis in a Diabetic Rat Model |
| Cryptotanshinone | 📋 | | | | 38371808 | Diterpenoid Tanshinones Can Inhibit Lung Cancer Progression by Improving the Tumor Microenvironment and Downregulation of NF-κB Expression |
| DHEA | 📋 | ✍ | ⛔ | | 38495508 | DHEA down-regulates mitochondrial dynamics and promotes apoptosis of lung adenocarcinoma cells through FASTKD2 |
| Eugenol | 📋 | | | | 38675465 | Eugenol Inhibits Neutrophils Myeloperoxidase In Vitro and Attenuates LPS-Induced Lung Inflammation in Mice |
| Fish Oil | 📋 | ✍ | ⛔ | | 36547898 | Targeting EGFR in Combination with Nutritional Supplements on Antitumor Efficacy in a Lung Cancer Mouse Model |
| Formononetin | 📋 | | | | 38230781 | Mechanisms analysis for Formononetin counteracted-Osimertinib resistance in non-small cell lung cancer cells: From the insight into the gene transcriptional level |
| Indian Gooseberry | 📋 | | ⛔ | | 38056150 | Tannins in Phyllanthus emblica L. improves cisplatin efficacy in lung cancer cells by boosting endoplasmic reticulum stress to trigger immunogenic cell death |
| L-Carnitine | 📋 | ✍ | ⛔ | | 37878885 | L-carnitine reduces acute lung injury via mitochondria modulation and inflammation control in pulmonary macrophages |
| Magnolol | 📋 | | | | 37282760 | Magnolol alleviates pulmonary fibrosis inchronic obstructive pulmonary disease by targeting transient receptor potential vanilloid 4-ankyrin repeat domain |
| Moringa Oleifera | 📋 | ✍ | ⛔ | | 37881795 | Moringa oleifera Use in Maintaining Oral Health and Its Potential Use in Regenerative Dentistry |
| Mulberry | 📋 | | ⛔ | | 38691297 | Pharmacological Properties of White Mulberry (Morus alba L.) Leaves: Suppressing Migratory and Invasive Activities Against A549 Lung Cancer Cells |
| Naringin | 📋 | ✍ | ⛔ | | 36746356 | Naringin protects mice from D-galactose-induced lung aging and mitochondrial dysfunction: Implication of SIRT1 pathways |
| Shogaol | 📋 | | | | 37638803 | 6-Shogaol prevents benzo (A) pyrene-exposed lung carcinogenesis via modulating PRDX1-associated oxidative stress, inflammation, and proliferation in mouse models |
| Aloe-Emodin | 📋 | | | | 36866539 | Aloe-emodin targets multiple signaling pathways by blocking ubiquitin-mediated degradation of DUSP1 in nasopharyngeal carcinoma cells |
| Beta-Sitosterol | 📋 | ✍ | ⛔ | | 38439529 | β-Sitosterol attenuates anlotinib resistance in non-small cell lung cancer cells by inhibiting miR-181a-3p/SHQ1 signaling |
| Blueberry | 📋 | ✍ | ⛔ | | 38715184 | Blueberry extract and its bioactive compounds mitigate oxidative stress and suppress human lung cancer cell (A549) growth by modulating the expression of p53/EGFR/STAT3/IL6-mediated signaling molecules |
| Carnosic Acid | 📋 | | | | 38396629 | Carnosic Acid against Lung Cancer: Induction of Autophagy and Activation of Sestrin-2/LKB1/AMPK Signalling |
| Dandelion | 📋 | ✍ | ⛔ | | 34727378 | Revealing the metabolic mechanism of dandelion extract against A549 cells using UPLC-QTOF MS |
| Escin | 📋 | ✍ | ⛔ | | 37579900 | Molecular regulation of autophagy and suppression of protein kinases by aescin, a triterpenoid saponin impedes lung cancer cell proliferation and mobility |
| Honokiol | 📋 | | | | 38626551 | Honokiol suppress the PD-L1 expression to improve anti-tumor immunity in lung cancer |
| Mangosteen | 📋 | ✍ | ⛔ | | 38034260 | Inhibition of Oral Fibrinogenesis Through Transforming Growth Factor-Beta/SMAD2/3 Signalling Inhibition Using Mangosteen Pericarp Extract |
| Silymarin | 📋 | ✍ | ⛔ | | 38372113 | The role of silymarin and MAPK pathway in the regulation of proliferation and invasion of non-small cell lung cancer cells |
| Tangeretin | 📋 | | | | 38147126 | Tangeretin attenuates acute lung injury in septic mice by inhibiting ROS-mediated NLRP3 inflammasome activation via regulating PLK1/AMPK/DRP1 signaling axis |
| Walnut | 📋 | | ⛔ | | 35401757 | Amelioration of Ovalbumin-Induced Allergic Asthma by Juglans regia via Downregulation of Inflammatory Cytokines and Upregulation of Aquaporin-1 and Aquaporin-5 in Mice |
| Withaferin A | 📋 | | | | 37370701 | Withaferin A Increases the Effectiveness of Immune Checkpoint Blocker for the Treatment of Non-Small Cell Lung Cancer |
| Acacetin | 📋 | | | | 38287075 | Acacetin inhibited non-small-cell lung cancer (NSCLC) cell growth via upregulating miR-34a in vitro and in vivo |
| Amygdalin | 📋 | ✍ | ⛔ | | 38085145 | Amygdalin Improves Allergic Asthma via the Thymic Stromal Lymphopoietin-dendritic Cell-OX40 Ligand Axis in a Mouse Model |
| Calycosin | 📋 | | | | 37635478 | Calycosin inhibits gemcitabine-resistant lung cancer cells proliferation through modulation of the LDOC1/GNL3L/NFκB |
| Catechins | 📋 | | | | 35938963 | Effect of epicatechin on inflammatory cytokines and MAPK/NF-κB signaling pathway in lipopolysaccharideinduced acute lung injury of BALB/c mice |
| Flavonoids | 📋 | | ⛔ | | 37664726 | Natural plant resource flavonoids as potential therapeutic drugs for pulmonary fibrosis |
| L-Citrulline | 📋 | ✍ | ⛔ | | 37349511 | L-citrulline attenuates lipopolysaccharide-induced inflammatory lung injury in neonatal rats |
| Paeoniflorin | 📋 | | | | 38705442 | Paeoniflorin attenuates particulate matter-induced acute lung injury by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis through activation of the Nrf2 signaling pathway |
| Punicalagin | 📋 | ✍ | ⛔ | | 36651367 | Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways |
| Vitamin B9 | 📋 | ✍ | ⛔ | | 38163975 | [Impact of Folic Acid on the Resistance of Non-small Cell Lung Cancer Cells to Osimertinib by Regulating Methylation of DUSP1] |
| Angelica | 📋 | ✍ | ⛔ | | 35682836 | Butylidenephthalide Abrogates the Snail-Induced Cancer Stemness in Oral Carcinomas |
| Antioxidants | 📋 | | ⛔ | | 38259449 | Association between dietary antioxidant levels and chronic obstructive pulmonary disease: a mediation analysis of inflammatory factors |
| Astragalin | 📋 | | | | 34817340 | Astragalin flavonoid inhibits proliferation in human lung carcinoma cells mediated via induction of caspase-dependent intrinsic pathway, ROS production, cell migration and invasion inhibition and targeting JAK/STAT signalling pathway |
| Boswellic Acid | 📋 | ✍ | ⛔ | | 38513840 | Acetyl-11-keto-beta-boswellic acid inhibits cell proliferation and growth of oral squamous cell carcinoma via RAB7B-mediated autophagy |
| Cordycepin | 📋 | | | | 38299286 | Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Cordycepin against Pulmonary Arterial Hypertension in Rats |
| Daidzein | 📋 | ✍ | ⛔ | | 37802433 | Inhibitory effect of daidzein on the calcium-activated chloride channel TMEM16A and its anti-lung adenocarcinoma activity |
| Eicosapentaenoic Acid | 📋 | ✍ | ⛔ | | 35355027 | N-3 PUFAs and their specialized pro-resolving lipid mediators on airway inflammatory response: beneficial effects in the prevention and treatment of respiratory diseases |
| Elderberry | 📋 | ✍ | ⛔ | | 33881685 | The impact of Sambucus nigra L. extract on inflammation, oxidative stress and tissue remodeling in a rat model of lipopolysaccharide-induced subacute rhinosinusitis |
| Food | 📋 | | | | 37764686 | The Possible Role of Food and Diet in the Quality of Life in Patients with COPD-A State-of-the-Art Review |
| Goji Berry | 📋 | ✍ | ⛔ | | 37119863 | Lycium barbarum polysaccharide-glycoprotein ameliorates ionizing radiation-induced epithelial injury by regulating oxidative stress and ferroptosis via the Nrf2 pathway |
| NMN | 📋 | ✍ | ⛔ | | 38100537 | Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway |
| Oleuropein | 📋 | | | | 34515957 | Ameliorative Effects of Oleuropein on Lipopolysaccharide-Induced Acute Lung Injury Model in Rats |
| Ollive Leaf extract | 📋 | ✍ | ⛔ | | 38508716 | Olea europaea L. leaf extract mitigates pulmonary inflammation and tissue destruction in Wistar rats induced by concurrent exposure to noise and toluene |
| Peony | 📋 | | ⛔ | | 37666859 | Exploring the role and mechanism of Astragalus membranaceus and radix paeoniae rubra in idiopathic pulmonary fibrosis through network pharmacology and experimental validation |
| Piperlongumine | 📋 | | | | 38452870 | Anti-cancer agent piperlongumine is an inhibitor of transient receptor potential melastatin 7 channel in oral squamous cell carcinoma |
| Raspberry | 📋 | ✍ | ⛔ | | 36556421 | Chemical Composition of Volatile Extracts from Black Raspberries, Blueberries, and Blackberries and Their Antiproliferative Effect on A549 Non-Small-Cell Lung Cancer Cells |
| Rutin | 📋 | ✍ | ⛔ | | 38126185 | Characterization of PKCα-rutin interactions and their application as a treatment strategy for pulmonary arterial hypertension by inhibiting ferroptosis |
| Spirulina | 📋 | ✍ | ⛔ | | 36789047 | Therapeutic efficacy of spirulina against ovalbumin and cigarette smoke-induced asthma-specific stress biomarkers in Sprague-Dawley rats |
| Tea | 📋 | | | | 36281921 | Association of Coffee and Tea Consumption with Cardiovascular Disease, Chronic Respiratory Disease, and their Comorbidity |
| Aspirin | 📋 | | ⛔ | | 38100146 | Aspirin boosts the synergistic effect of EGFR/p53 inhibitors on lung cancer cells by regulating AKT/mTOR and p53 pathways |
| Bee Venom | 📋 | ✍ | ⛔ | | 38041592 | Melittin kills A549 cells by targeting mitochondria and blocking mitophagy flux |
| Beets | 📋 | ✍ | ⛔ | | 38123239 | Oral nitrate supplementation improves cardiovascular risk markers in COPD: ON-BC a randomised controlled trial |
| Beta-Carotene | 📋 | ✍ | ⛔ | | 38107596 | The Associations Between Serum Vitamins and Carotenoids with Chronic Obstructive Pulmonary Disease: Results from the NHANES |
| Black Tea | 📋 | ✍ | ⛔ | | 37940573 | The Effects of Black Tea Consumption on Intestinal Microflora-A Randomized Single-Blind Parallel-Group, Placebo-Controlled Study |
| Carotenoids | 📋 | ✍ | ⛔ | | 38259449 | Association between dietary antioxidant levels and chronic obstructive pulmonary disease: a mediation analysis of inflammatory factors |
| Dioscin | 📋 | | | | 38356707 | Dioscin inhibits non-small cell lung cancer cells and activates apoptosis by downregulation of Survivin |
| Eucalyptus | 📋 | ✍ | ⛔ | | 35834630 | Protective Effect of Eucalyptus globulus Extracts Against Bleomycin-Induced Pulmonary Fibrosis in Rats |
| Fenugreek | 📋 | ✍ | ⛔ | | 37885997 | Promoting cardioprotection with fenugreek: Insights from CoCl2-induced hypoxia in neonatal rat cardiomyocytes |
| Ferulic Acid | 📋 | ✍ | ⛔ | | 38643862 | Network pharmacology-based research into the mechanism of ferulic acid on acute lung injury through enhancing transepithelial sodium transport |
| Glycyrrhetinic Acid | 📋 | | | | 38401519 | Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis |
| Icaritin | 📋 | | | | 38294683 | Atomized inhalation of Icaritin reduces airway inflammation and remodeling in asthmatic mice |
| Isorhamnetin | 📋 | | | | 37839759 | Isorhamnetin as a novel inhibitor of pneumolysin against Streptococcus pneumoniae infection in vivo/in vitro |
| MSM | 📋 | ✍ | ⛔ | | 35561750 | Methylsulfonylmethane relieves cobalt chloride-induced hypoxic toxicity in C2C12 myoblasts |
| Patchouli | 📋 | ✍ | ⛔ | | 37249164 | Patchouli alcohol induces G0 /G1 cell cycle arrest and apoptosis in vincristine-resistant non-small cell lung cancer through ROS-mediated DNA damage |
| Pomegranate Peel extract | 📋 | ✍ | ⛔ | | 33834138 | Comparison of antifungal efficacy of ethanolic extracts of Woodfordia fruticosa leaf and Punica granatum peel in uncontrolled diabetic patients wearing removable dentures: A randomized controlled clinical trial |
| Saffron | 📋 | ✍ | ⛔ | | 37827264 | The effects of Crocus sativus extract on inhaled paraquat-induced lung inflammation, oxidative stress, pathological changes and tracheal responsiveness in rats |
| Scutellarin | 📋 | | | | 38168709 | Scutellarin Alleviates Ovalbumin-Induced Airway Remodeling in Mice and TGF-β-Induced Pro-fibrotic Phenotype in Human Bronchial Epithelial Cells via MAPK and Smad2/3 Signaling Pathways |
| Sea Buckthorn | 📋 | ✍ | ⛔ | | 35627086 | Chemosensitization Effect of Seabuckthorn ( Hippophae rhamnoides L.) Pulp Oil via Autophagy and Senescence in NSCLC Cells |
| Sesamol | 📋 | | | | 37462223 | Sesamol attenuates bleomycin-induced pulmonary toxicity and fibrosis in experimental animals |
| Thymol | 📋 | ✍ | ⛔ | | 37655051 | Thymol targeting interleukin 4 induced 1 expression reshapes the immune microenvironment to sensitize the immunotherapy in lung adenocarcinoma |
| Aloin | 📋 | | | | 37781715 | Exploration of the mechanism of aloin ameliorates of combined allergic rhinitis and asthma syndrome based on network pharmacology and experimental validation |
| Arjuna | 📋 | ✍ | ⛔ | | 28618017 | Curcumin and metformin-mediated chemoprevention of oral cancer is associated with inhibition of cancer stem cells |
| Beta-Glucan | 📋 | ✍ | ⛔ | | 38603862 | β-glucan mitigates ovalbumin-induced airway inflammation by preventing oxidative stress and CD8+ T cell infiltration |
| Black Tea Polyphenols | 📋 | | | | 36008552 | Prevention of carcinogen-induced oral cancers by polymeric black tea polyphenols via modulation of EGFR-Akt-mTOR pathway |
| Camellia | 📋 | | ⛔ | | 38606171 | Phytochemical analysis and anticancer effect of Camellia oleifera bud ethanol extract in non-small cell lung cancer A549 cells |
| CAPE | 📋 | | | | 38000688 | Caffeic Acid Phenethyl Ester (CAPE), a natural polyphenol to increase the therapeutic window for lung adenocarcinomas |
| Cinnamon Essential Oil | 📋 | ✍ | ⛔ | | 34572724 | Antibiofilm Potential of Medicinal Plants against Candida spp. Oral Biofilms: A Review |
| Cocoa | 📋 | ✍ | ⛔ | | 37764711 | Biological Properties and Antimicrobial Potential of Cocoa and Its Effects on Systemic and Oral Health |
| Diosgenin | 📋 | | | | 38458369 | Potential targets of diosgenin for the treatment of oral squamous cell carcinoma and their bioinformatics and transcriptional profiling analyses |
| Diosmin | 📋 | ✍ | ⛔ | | 35920545 | Chemopreventive potential of Diosmin against benzo[a]pyrene induced lung carcinogenesis in Swiss Albino mice |
| Echinacoside | 📋 | | | | 38001778 | Sirtuin1 Mediates the Protective Effects of Echinacoside against Sepsis-Induced Acute Lung Injury via Regulating the NOX4-Nrf2 Axis |
| Frankincense | 📋 | ✍ | ⛔ | | 37109265 | A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study |
| Ginkgolic Acid | 📋 | | | | 35707278 | Ginkgolic acid improves bleomycin-induced pulmonary fibrosis by inhibiting SMAD4 SUMOylation |
| Hyaluronic Acid | 📋 | ✍ | ⛔ | | 37920632 | Hyaluronic Acid: Exploring Its Versatile Applications in Dentistry |
| Hydroxytyrosol | 📋 | | | | 38281774 | Hydroxytyrosol Alleviates Methotrexate-Induced Pulmonary Fibrosis in Rats: Involvement of TGF-β1, Tissue Factor, and VEGF |
| Irisin | 📋 | | | | 38143500 | Potential role of irisin in lung diseases and advances in research |
| Isoliquiritigenin | 📋 | | | | 37930332 | Isoliquiritigenin Inhibits Oral Squamous Cell Carcinoma and Overcomes Chemoresistance by Destruction of Survivin |
| Ligustilide | 📋 | | | | 38069368 | Z-Ligustilide Combined with Cisplatin Reduces PLPP1-Mediated Phospholipid Synthesis to Impair Cisplatin Resistance in Lung Cancer |
| Neferine | 📋 | | | | 37698291 | Neferine inhibits the development of lung cancer cells by downregulating TGF-β to regulate MST1/ROS-induced pyroptosis |
| Perilla | 📋 | ✍ | | | 37834377 | Therapeutic Effects of Perilla Phenols in Oral Squamous Cell Carcinoma |
| Rapamycin | 📋 | ✍ | | | 38276004 | Rapamycin as a Potential Alternative Drug for Squamous Cell Gingiva Carcinoma (Ca9-22): A Focus on Cell Cycle, Apoptosis and Autophagy Genetic Profile |
| Retinoic Acid | 📋 | | | | 38612663 | Retinoic Acid Treatment Mitigates PM2.5-Induced Type 2 Inflammation: Insights into Modulation of Innate Immune Responses |
| Rosemary | 📋 | ✍ | ⛔ | | 38481883 | Anticancer Effects of Rosmarinus officinalis Leaf Extract on KB Cell Lines |
| Stigmasterol | 📋 | | | | 38579176 | Stigmasterol alleviates airway inflammation in OVA-induced asthmatic mice via inhibiting the TGF-β1/Smad2 and IL-17A signaling pathways |
| Tannic Acid | 📋 | ✍ | ⛔ | | 37947914 | Dietary tannic acid attenuates elastase-induced pulmonary inflammation and emphysema in mice |
| Taurine | 📋 | ✍ | ⛔ | | 29078374 | Taurine Ameliorates Particulate Matter-Induced Emphysema by Switching on Mitochondrial NADH Dehydrogenase Genes |
| Vitamin B6 | 📋 | ✍ | ⛔ | | 31970902 | Vitamin B6 inhibits macrophage activation to prevent lipopolysaccharide-induced acute pneumonia in mice |
| Vitamin K | 📋 | ✍ | ⛔ | | 36835797 | The Pleiotropic Role of Vitamin K in Multimorbidity of Chronic Obstructive Pulmonary Disease |
| Zingerone | 📋 | | | | 37605724 | Protective effects of zingerone against sodium arsenite-induced lung toxicity: A multi-biomarker approach |
| Anethole | 📋 | | | | 37242484 | Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways |
| Anthocyanins | 📋 | ✍ | ⛔ | | 38716355 | Anthocyanins prevent the development and progression of urethane-induced lung cancer by regulating energy metabolism in mice |
| Barberry | 📋 | ✍ | ⛔ | | 37315644 | Buccal spray of standardized Berberis aristata extract causes tumour regression, chemoprotection and downregulation of inflammatory mediators in oral cancer hamster model |
| Beta-Cryptoxanthin | 📋 | | | | 37049698 | Anti-Inflammatory Effects of β-Cryptoxanthin on 5-Fluorouracil-Induced Cytokine Expression in Human Oral Mucosal Keratinocytes |
| Beta-Lapachone | 📋 | | | | 38604545 | β-Lapachone, an NQO1 bioactivatable drug, prevents lung tumorigenesis in mice |
| Betaine | 📋 | ✍ | ⛔ | | 37970921 | Anti-inflammatory and antioxidant properties of betaine protect against sepsis-induced acute lung injury: CT and histological evidence |
| Chrysanthemum | 📋 | ✍ | ⛔ | | 36777434 | Effect of ethanol extract from Chrysanthemum cinerariifolium leaves on Ki-67 proliferation and dysplasia severity in a rat model of oral squamous cell carcinoma |
| Clove | 📋 | | ⛔ | | 38650159 | In vivo determination of the anti-inflammatory and antioxidant effects of the aqueous extract of Syzygium aromaticum (clove) in an asthmatic rat model |
| Coffee | 📋 | ✍ | ⛔ | | 37529275 | Effects of coffee intake on airway hypersensitivity and immunomodulation: an in vivo murine study |
| Eleuthero | 📋 | ✍ | ⛔ | | 37776644 | Protective effects of Eleutheroside E against high-altitude pulmonary edema by inhibiting NLRP3 inflammasome-mediated pyroptosis |
| Ginger extract | 📋 | ✍ | ⛔ | | 28652934 | Phytochemical-rich medicinal plant extracts suppress bacterial antigens-induced inflammation in human tonsil epithelial cells |
| Ginkgetin | 📋 | | | | 36937843 | Integrating network pharmacology prediction and experimental investigation to verify ginkgetin anti-invasion and metastasis of human lung adenocarcinoma cells via the Akt/GSK-3β/Snail and Wnt/β-catenin pathway |
| Gotu Kola | 📋 | ✍ | ⛔ | | 37247290 | Evaluation of the Anti-Carcinogenic Effect of Centella Asiatica on Oral Cancer Cell Line: In vitro Study |
| Graviola | 📋 | ✍ | ⛔ | | 38075540 | In vitro Evaluation of Cytotoxic Effects of Methanolic Leaf Extracts of Annona muricata on Oral Squamous Cell Carcinoma-15 Cell Lines and its Effect On Expression of Bcl 2-associated X protein, B-cell C/Lymphoma 2 and p53 Genes |
| Kiwifruit | 📋 | ✍ | ⛔ | | 36328432 | [Unsaturated fatty acid of Actinidia chinesis planch seed oil protects against pulmonary fibrosis by inhibiting collagen synthesis via down-regulating connective tissue growth factor (CTGF) expression in rats] |
| Knotweed | 📋 | ✍ | ⛔ | | 37569890 | Fallopia japonica Root Extract Ameliorates Ovalbumin-Induced Airway Inflammation in a CARAS Mouse Model by Modulating the IL-33/TSLP/NF-κB Signaling Pathway |
| Loquat | 📋 | ✍ | ⛔ | | 34438032 | Theory of the exterior-interior relationship between the lungs and the large intestine to explore the mechanism of Eriobotrya japonica leaf water extract in the treatment of cough variant asthma |
| Lutein | 📋 | ✍ | ⛔ | | 38457968 | Association between carotenoids and the prevalence of chronic obstructive pulmonary disease in the United States |
| Morusin | 📋 | | | | 33035517 | Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells |
| Onion | 📋 | ✍ | ⛔ | | 38584568 | Treatment with onion bulb extract both prevents and reverses allergic inflammation in a murine model of asthma |
| Prebiotics | 📋 | ✍ | ⛔ | | 38304119 | Manipulating the diseased oral microbiome: the power of probiotics and prebiotics |
| PUFA | 📋 | | | | 37094679 | Dietary polyunsaturated fatty acids intake, air pollution, and the risk of lung cancer: A prospective study in UK biobank |
| Senolytics | 📋 | | | | 37442061 | Cellular senescence in asthma: from pathogenesis to therapeutic challenges |
| Stinging Nettle | 📋 | ✍ | ⛔ | | 30899059 | Urtica dioica L. inhibits proliferation and enhances cisplatin cytotoxicity in NSCLC cells via Endoplasmic Reticulum-stress mediated apoptosis |
| Tetrahydrocurcumin | 📋 | ✍ | | | 35723652 | Tetrahydrocurcumin Ameliorates Acute Hypobaric Hypoxia-Induced Cognitive Impairment in Mice |
| Theaflavins | 📋 | ✍ | | | 35656444 | Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro |
| Tribulus Terrestris | 📋 | ✍ | ⛔ | | 38725454 | Tribuloside: Mechanisms and Efficacy in Treating Acute Lung Injury Revealed by Network Pharmacology and Experimental Validation |
| Urolithins | 📋 | | | | 38319388 | Urolithin A exerts a protective effect on lipopolysaccharide-induced acute lung injury by regulating HMGB1-mediated MAPK and NF-κB signaling pathways |
| Vitamin B8 | 📋 | ✍ | ⛔ | | 37194070 | Inositol possesses antifibrotic activity and mitigates pulmonary fibrosis |
| Vitamins | 📋 | | | | 38456156 | An inverse causal relationship between serum 25-hydroxyvitamin D levels and pulmonary hypertension: A two-sample Mendelian randomization study |
| Acai Berry | 📋 | ✍ | ⛔ | | 35551733 | Açaí (Euterpe Oleraceae Mart.) Seeds Regulate NF-κB and Nrf2/ARE Pathways Protecting Lung against Acute and Chronic Inflammation |
| Aged Garlic | 📋 | ✍ | ⛔ | | 28353632 | Attenuation of Bleomycin-Induced Pulmonary Fibrosis in Rats with S-Allyl Cysteine |
| Apple Polyphenols | 📋 | | ⛔ | | 31257800 | [Effects of apple polyphenols on monocrotaline-induced pulmonary vascular remodeling in rats and its mechanism] |
| Basil | 📋 | ✍ | ⛔ | | 35046828 | The Effect of Ocimum basilicum L. and Its Main Ingredients on Respiratory Disorders: An Experimental, Preclinical, and Clinical Review |
| Betulinic Acid | 📋 | | | | 34267658 | Combination Treatment With Inhibitors of ERK and Autophagy Enhances Antitumor Activity of Betulinic Acid in Non-small-Cell Lung Cancer In Vivo and In Vitro |
| Biochanin A | 📋 | | | | 38266663 | Biochanin A - A G6PD inhibitor: In silico and in vitro studies in non-small cell lung cancer cells (A549) |
| Carnosol | 📋 | | | | 38414287 | Carnosol alleviates sepsis-induced pulmonary endothelial barrier dysfunction by targeting nuclear factor erythroid2-related factor 2/sirtuin-3 signaling pathway to attenuate oxidative damage |
| Citicoline | 📋 | ✍ | ⛔ | | 33606602 | Postexposure Liponucleotide Prophylaxis and Treatment Attenuates Acute Respiratory Distress Syndrome in Influenza-infected Mice |
| Citrus Fruits | 📋 | | ⛔ | | 37850547 | Citrus peel extract protects against diesel exhaust particle-induced chronic obstructive pulmonary disease-like lung lesions and oxidative stress |
| Coconut Oil | 📋 | | ⛔ | | 32952561 | Coconut Oil as a Novel Approach to Managing Radiation-Induced Xerostomia: A Primary Feasibility Study |
| Coptis Chinensis | 📋 | | ⛔ | | 38729536 | Coptidis rhizoma extract alleviates oropharyngeal candidiasis by gC1qR-EGFR/ERK/c-fos axis-induced endocytosis of oral epithelial cells |
| Cranberry | 📋 | ✍ | ⛔ | | 37375955 | The Protective Role of Cranberries and Blueberries in Oral Cancer |
| D-Limonene | 📋 | ✍ | ⛔ | | 38309095 | Eucalyptol, limonene and pinene enteric capsules attenuate airway inflammation and obstruction in lipopolysaccharide-induced chronic bronchitis rat model via TLR4 signaling inhibition |
| Fiber | 📋 | ✍ | ⛔ | | 38442136 | Association Between Dietary Fiber Intake and Prevalence of Chronic Obstructive Pulmonary Disease in a Middle-Aged and Elderly Population: a Study Based on the National Health and Nutrition Examination Survey Database |
| Fish | 📋 | | ⛔ | | 35334852 | Diet and Respiratory Infections: Specific or Generalized Associations? |
| Fruits | 📋 | | | | 36911739 | Dietary factors and risk for asthma: A Mendelian randomization analysis |
| Gamma-Linolenic Acid | 📋 | ✍ | ⛔ | | 32623575 | Gamma Linolenic Acid Suppresses Hypoxia-Induced Proliferation and Invasion of Non-Small Cell Lung Cancer Cells by Inhibition of HIF1α |
| Geraniol | 📋 | | | | 35517879 | Autophagy/ Apoptosis Induced by Geraniol through HIF-1α/BNIP3/Beclin-1 Signaling Pathway in A549 CoCl2 Treated Cells |
| Glabridin | 📋 | | | | 37584465 | Immunomodulatory effect of glabridin in ovalbumin induced allergic asthma and its comparison with methylprednisolone in a preclinical rodent model |
| Guggulsterone | 📋 | | | | 38609738 | Guggulsterone protects against cigarette smoke-induced COPD linked lung inflammation |
| Isoflavones | 📋 | ✍ | ⛔ | | 35913505 | Isoflavone and soy food intake and risk of lung cancer in never smokers: report from prospective studies in Japan and China |
| Jujube | 📋 | | ⛔ | | 37524664 | Anti-inflammatory Effects of Ziziphus Jujube Mill on LPS-induced Acute Lung Injury in Mice |
| Linalool | 📋 | | ⛔ | | 38096923 | Analgesic effect of linalool odor on oral ulcerative mucositis-induced pain in rats |
| Liquiritigenin | 📋 | | | | 38238857 | The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin |
| Milk Thistle | 📋 | ✍ | ⛔ | | 34968721 | Milk thistle (Silybum marianum (L.)Gaertn.): An overview about its pharmacology and medicinal uses with an emphasis on oral diseases |
| Nattokinase | 📋 | ✍ | ⛔ | | 34717590 | Nattokinase crude extract enhances oral mucositis healing |
| Neem | 📋 | ✍ | | | 38585261 | The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study |
| Nimbolide | 📋 | | | | 38561609 | The Neem Limonoid Nimbolide Modulates Key Components of the DNA Damage Response Signalling in Cellular and Animal Models of Oral Squamous Cell Carcinoma |
| Oolong Tea | 📋 | | ⛔ | | 35873431 | Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China |
| Paeonol | 📋 | | | | 38265681 | Paeonol upregulates expression of tumor suppressors TNNC1 and SCARA5, exerting anti-tumor activity in non-small cell lung cancer cells |
| Peppermint Essential Oil | 📋 | ✍ | ⛔ | | 36864527 | Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial |
| Phytoestrogens | 📋 | | ⛔ | | 34684599 | Dietary Phytoestrogens Ameliorate Hydrochloric Acid-Induced Chronic Lung Injury and Pulmonary Fibrosis in Mice |
| Polyphenols | 📋 | | | | 37830192 | Recent Advancement and Novel Application of Natural Polyphenols for the Treatment of Allergy Asthma: From Phytochemistry to Biological Implications |
| PQQ | 📋 | ✍ | ⛔ | | 38613355 | Pyrroloquinoline quinone ameliorates PM2.5-induced pulmonary fibrosis through targeting epithelial-mesenchymal transition |
| Rosavin | 📋 | | ⛔ | | 38339153 | Rosavin Alleviates LPS-Induced Acute Lung Injure by Modulating the TLR-4/NF-κB/MAPK Singnaling Pathways |
| Sodium Bicarbonate | 📋 | ✍ | ⛔ | | 36597048 | Prevention and the treatment of oral mucositis: the efficacy of sodium bicarbonate vs other agents: a systematic review |
| St. Johns Wort | 📋 | ✍ | ⛔ | | 33964648 | Evaluation of the chemopreventive effects of Hypericum perforatum L on DMBA-applied rat oral mucosa |
| Tomato | 📋 | | ⛔ | | 34531702 | Tomatidine Improves Pulmonary Inflammation in Mice with Acute Lung Injury |
| Wormwood | 📋 | ✍ | ⛔ | | 36501380 | Aqueous Extract of Artemisia annua Shows In Vitro Antimicrobial Activity and an In Vivo Chemopreventive Effect in a Small-Cell Lung Cancer Model |
| Apple | 📋 | | ⛔ | | 33747463 | Boysenberry and apple juice concentrate reduced acute lung inflammation and increased M2 macrophage-associated cytokines in an acute mouse model of allergic airways disease |
| Arctiin | 📋 | | | | 38546350 | The protective effects of Arctiin in asthma by attenuating airway inflammation and inhibiting p38/NF-κB signaling |
| Asafoetida | 📋 | ✍ | ⛔ | | 36568408 | Molecular mechanism of Ferula asafoetida for the treatment of asthma: Network pharmacology and molecular docking approach |
| Atractylodes | 📋 | ✍ | ⛔ | | 37641404 | Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin |
| Bitter Melon | 📋 | ✍ | ⛔ | | 35267362 | Microwave- and Ultrasound-Assisted Extraction of Cucurbitane-Type Triterpenoids from Momordica charantia L. Cultivars and Their Antiproliferative Effect on SAS Human Oral Cancer Cells |
| Black Pepper | 📋 | ✍ | ⛔ | | 38601803 | Discovery of potential epidermal growth factor receptor inhibitors from black pepper for the treatment of lung cancer: an in-silico approach |
| Caffeic Acid | 📋 | ✍ | ⛔ | | 36751276 | Priming with caffeic acid enhances the potential and survival ability of human adipose-derived stem cells to counteract hypoxia |
| Cardamonin | 📋 | | | | 34890758 | Cardamonin attenuates phorbol 12-myristate 13-acetate-induced pulmonary inflammation in alveolar macrophages |
| Catalpol | 📋 | | | | 35685407 | Catalpol Attenuates Pulmonary Fibrosis by Inhibiting Ang II/AT 1 and TGF-β/Smad-Mediated Epithelial Mesenchymal Transition |
| Chokeberry | 📋 | ✍ | ⛔ | | 34846271 | Can the chokeberry juice be used as additional therapy for burning mouth syndrome in menopausal women? |
| Clove Essential Oil | 📋 | | ⛔ | | 35744988 | Pinus sylvestris L. and Syzygium aromaticum (L.) Merr. & L. M. Perry Essential Oils Inhibit Endotoxin-Induced Airway Hyperreactivity despite Aggravated Inflammatory Mechanisms in Mice |
| Coriander Essential Oil | 📋 | ✍ | ⛔ | | 37653637 | Chemical Composition, In vitro and In silico evaluation of essential oil from Ocimum tenuiflorum and Coriandrum sativum Linn for lung cancer |
| Diallyl Disulfide | 📋 | | | | 37956253 | Diallyl Disulfide Blocks Cigarette Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Lung Tumorigenesis via Activation of the Nrf2 Antioxidant System and Suppression of NF-κB Inflammatory Response |
| Diallyl Sulfide | 📋 | | | | 34888630 | Tobacco carcinogen 4-[methyl(nitroso)amino]-1-(3-pyridinyl)-1-butanone (NNK) drives metabolic rewiring and epigenetic reprograming in A/J mice lung cancer model and prevention with diallyl sulphide (DAS) |
| Eucalyptol | 📋 | | | | 35964659 | Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization |
| Eucalyptus Essential Oil | 📋 | | ⛔ | | 35834630 | Protective Effect of Eucalyptus globulus Extracts Against Bleomycin-Induced Pulmonary Fibrosis in Rats |
| Fennel | 📋 | ✍ | ⛔ | | 33497736 | Network pharmacology and molecular docking reveal the mechanism of Scopoletin against non-small cell lung cancer |
| Fig | 📋 | | ⛔ | | 36762489 | Latex derived from Ficus carica L. inhibited the growth of NSCLC by regulating the caspase/gasdermin/AKT signaling pathway |
| Fo-Ti Root | 📋 | ✍ | ⛔ | | 36267283 | 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways |
| Forskolin | 📋 | ✍ | ⛔ | | 34393799 | Isoforskolin Alleviates AECOPD by Improving Pulmonary Function and Attenuating Inflammation Which Involves Downregulation of Th17/IL-17A and NF-κB/NLRP3 |
| Ganoderic Acid | 📋 | | | | 38330446 | Ganoderic acid A suppresses autophagy by regulating the circFLNA/miR-486-3p/CYP1A1/XRCC1 axis to strengthen the sensitivity of lung cancer cells to cisplatin |
| Gardenia | 📋 | | ⛔ | | 34674717 | Huanglianjiedu Decoction as an effective treatment for oral squamous cell carcinoma based on network pharmacology and experimental validation |
| Guava | 📋 | | ⛔ | | 35906612 | The effect of hydroalcoholic extract of Psidium guajava L. on experimentally induced oral mucosal wound in rat |
| HMB | 📋 | ✍ | ⛔ | | 37739730 | Efficacy of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for the prevention of mucositis induced by platinum-based chemoradiation in head and neck cancer: A phase II study |
| Hyperoside | 📋 | | | | 37545738 | Hyperoside Attenuates Sepsis-Induced Acute Lung Injury (ALI) through Autophagy Regulation and Inflammation Suppression |
| Iodine | 📋 | ✍ | ⛔ | | 38305374 | Clinical Efficacy of Different Concentrations of Povidone Iodine in the Management of Peri-Implant Mucositis |
| L-Carnosine | 📋 | ✍ | ⛔ | | 36552670 | L-carnosine Attenuates Bleomycin-Induced Oxidative Stress via NFκB Pathway in the Pathogenesis of Pulmonary Fibrosis |
| Lavender Essential Oil | 📋 | ✍ | ⛔ | | 35991803 | The Effects of Lavender Essential Oil and its Clinical Implications in Dentistry: A Review |
| Lemongrass | 📋 | ✍ | ⛔ | | 38399374 | Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review |
| Lemongrass Essential Oil | 📋 | ✍ | ⛔ | | 34572724 | Antibiofilm Potential of Medicinal Plants against Candida spp. Oral Biofilms: A Review |
| Liquiritin | 📋 | | | | 37013552 | Liquiritin exhibits anti-acute lung injury activities through suppressing the JNK/Nur77/c-Jun pathway |
| Lotus | 📋 | | ⛔ | | 34724865 | Protective effects of lotus plumule ethanol extracts on bleomycin-induced pulmonary fibrosis in mice |
| Magnolia | 📋 | ✍ | ⛔ | | 37959865 | Effects of the Supercritical Fluid Extract of Magnolia figo on Inducing the Apoptosis of Human Non-Small-Cell Lung Cancer Cells |
| Mastic | 📋 | ✍ | ⛔ | | 37865987 | Sialagogic Effects Through Olfactory Stimulation with Mastic Resin and α-pinene Volatiles in vivo |
| Motherwort | 📋 | ✍ | ⛔ | | 38134637 | Protective effect of the mixture of Lactiplantibacillus plantarum KC3 and Leonurus Japonicas Houtt extract on respiratory disorders |
| Nicotinamide | 📋 | ✍ | ⛔ | | 38593249 | Nicotinamide in Combination with EGFR-TKIs for the Treatment of Stage IV Lung Adenocarcinoma with EGFR Mutations: A Randomized Double-Blind (Phase IIb) Trial |
| Olive Oil | 📋 | ✍ | ⛔ | | 33996432 | Assessing the topical application efficiency of two biological agents in managing chemotherapy-induced oral mucositis in children: A randomized clinical trial |
| Parthenolide | 📋 | | | | 32705224 | Parthenolide inhibits human lung cancer cell growth by modulating the IGF‑1R/PI3K/Akt signaling pathway |
| Phloretin | 📋 | | | | 35853279 | The inhibition of GLUT1-induced glycolysis in macrophage by phloretin participates in the protection during acute lung injury |
| Pomelo | 📋 | | ⛔ | | 37436082 | Ethanol Extract of Citrus grandis 'Tomentosa' Exerts Anticancer Effects by Targeting Skp2/p27 Pathway in Non-Small Cell Lung Cancer |
| Proanthocyanidins | 📋 | | | | 36526043 | Proanthocyanidins attenuates ferroptosis against influenza-induced acute lung injury in mice by reducing IFN-γ |
| Procyanidins | 📋 | | ⛔ | | 37175637 | Procyanidin B2 Attenuates Sepsis-Induced Acute Lung Injury via Regulating Hippo/Rho/PI3K/NF-κB Signaling Pathway |
| Quercitrin | 📋 | | | | 35799602 | Quercitrin protects human bronchial epithelial cells from oxidative damage |
| Roselle | 📋 | ✍ | ⛔ | | 38376437 | Antioxidant and Antineoplastic Activities of Hibiscus sabdariffa Linn. Petal Extracts against Oral Squamous Cell Carcinoma Cell Line |
| Royal Jelly | 📋 | ✍ | ⛔ | | 35158127 | Royal jelly regulates the caspase, Bax and COX-2, TNF-α protein pathways in the fluoride exposed lung damage in rats |
| Safranal | 📋 | | | | 34093515 | Safranal Alleviated OVA-Induced Asthma Model and Inhibits Mast Cell Activation |
| Sage | 📋 | ✍ | ⛔ | | 36889292 | Reduction of viral load in patients with acute sore throats: Results from an observational clinical trial with Echinacea / Salvia lozenges |
| Salt | 📋 | | ⛔ | | 35642398 | Effect of rock salt aerosol therapy on quality of life of patients with pneumoconiosis: A multicenter, randomized, double-blind clinical trial |
| Sea Cucumber | 📋 | | | | 38611791 | Sea Cucumber and Blueberry Extracts Suppress Inflammation and Reduce Acute Lung Injury through the Regulation of NF-κB/MAPK/JNK Signaling Pathway in Lipopolysaccharide-Treated C57BL/6 Mice |
| Sesamin | 📋 | ✍ | | | 36735045 | Sesamin Induces the Transdifferentiation of Type II Alveolar Epithelial Cells via AnnexinA1 and TRPV1 |
| Star Anise | 📋 | ✍ | ⛔ | | 34195261 | Crossover Analysis of the Astringent, Antimicrobial, and Anti-inflammatory Effects of Illicium verum/Star Anise in the Oral Cavity |
| Tea Polyphenols | 📋 | | | | 38501424 | [Tea polyphenols ameliorates acute lung injury in septic mice by inhibiting NLRP3 inflammasomes] |
| Theabrownins | 📋 | | | | 37274480 | Gallic acid in theabrownin suppresses cell proliferation and migration in non‑small cell lung carcinoma via autophagy inhibition |
| Theobromine | 📋 | ✍ | ⛔ | | 30820200 | Effect of theobromine in antimicrobial activity: An in vitro study |
| Thyme Essential Oil | 📋 | | ⛔ | | 34111725 | Thyme oil alleviates Ova-induced bronchial asthma through modulating Th2 cytokines, IgE, TSLP and ROS |
| UDCA | 📋 | ✍ | ⛔ | | 37948864 | Ursodeoxycholic acid alleviates sepsis-induced lung injury by blocking PANoptosis via STING pathway |
| Vitexin | 📋 | | | | 35026520 | Vitexin restores lung homeostasis by targeting vicious loop between inflammatory aggravation and autophagy mediated via multiple redox cascade and myeloid cells alteration in experimental allergic asthma |
| Anthocyanidins | 📋 | | | | 35887251 | Insights into the Mechanisms of Action of Proanthocyanidins and Anthocyanins in the Treatment of Nicotine-Induced Non-Small Cell Lung Cancer |
| Apricot Kernels | 📋 | ✍ | ⛔ | | 31110425 | Effect of Amygdalin on Oral Cancer Cell Line: An in vitro Study |
| Arachidonic Acid | 📋 | ✍ | ⛔ | | 36432203 | Integrative Analysis of Proteomics and Metabolism Reveals the Potential Roles of Arachidonic Acid Metabolism in Hypoxia Response in Mouse Spleen |
| Avocado | 📋 | ✍ | ⛔ | | 21596018 | Aliphatic acetogenin constituents of avocado fruits inhibit human oral cancer cell proliferation by targeting the EGFR/RAS/RAF/MEK/ERK1/2 pathway |
| BCAA | 📋 | ✍ | ⛔ | | 36820928 | High dose isoleucine stabilizes nuclear PTEN to suppress the proliferation of lung cancer |
| Bergamot Essential Oil | 📋 | ✍ | ⛔ | | 37267637 | Bergapten ameliorates combined allergic rhinitis and asthma syndrome after PM2.5 exposure by balancing Treg/Th17 expression and suppressing STAT3 and MAPK activation in a mouse model |
| Bilberry | 📋 | ✍ | ⛔ | | 34439567 | Bilberry ( Vaccinium myrtillus L.) Powder Has Anticarcinogenic Effects on Oral Carcinoma In Vitro and In Vivo |
| Blackberry | 📋 | | ⛔ | | 36556421 | Chemical Composition of Volatile Extracts from Black Raspberries, Blueberries, and Blackberries and Their Antiproliferative Effect on A549 Non-Small-Cell Lung Cancer Cells |
| Blackcurrant | 📋 | ✍ | ⛔ | | 37109265 | A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study |
| Burdock | 📋 | | ⛔ | | 38068804 | Preventive Effect of Arctium lappa Polysaccharides on Acute Lung Injury through Anti-Inflammatory and Antioxidant Activities |
| Butter | 📋 | | ⛔ | | 37886368 | Association between Butter, Margarine, and Olive Oil Intake and Asthma Symptoms among School Children: Result from a Large-Scale Cross-Sectional Study |
| Calcium D-Glucarate | 📋 | ✍ | ⛔ | | 22870144 | Dietary D-glucarate effects on the biomarkers of inflammation during early post-initiation stages of benzo[a]pyrene-induced lung tumorigenesis in A/J mice |
| Cat's Claw | 📋 | ✍ | ⛔ | | 29432856 | Aqueous extracts from Uncaria tomentosa (Willd. ex Schult.) DC. reduce bronchial hyperresponsiveness and inflammation in a murine model of asthma |
| Chili Pepper | 📋 | | ⛔ | | 35600864 | The Antifibrotic and the Anticarcinogenic Activity of Capsaicin in Hot Chili Pepper in Relation to Oral Submucous Fibrosis |
| Choline | 📋 | ✍ | ⛔ | | 32797252 | Choline in cystic fibrosis: relations to pancreas insufficiency, enterohepatic cycle, PEMT and intestinal microbiota |
| Cinnamic Acid | 📋 | | | | 37581637 | Cinnamic acid mitigates methotrexate-induced lung fibrosis in rats: comparative study with pirfenidone |
| Colostrum | 📋 | ✍ | ⛔ | | 37630816 | Six Weeks of Supplementation with Bovine Colostrum Effectively Reduces URTIs Symptoms Frequency and Gravity for Up to 20 Weeks in Pre-School Children |
| Conjugated Linoleic Acid | 📋 | ✍ | ⛔ | | 37001725 | Conjugated linoleic acid strengthens the apoptotic effect of cisplatin in A549 cells |
| Creatine | 📋 | ✍ | ⛔ | | 17273571 | New Treatments for Chronic Obstructive Pulmonary Disease Using Ergogenic Aids |
| Diallyl Trisulfide | 📋 | | | | 38086660 | Diallyl trisulfide inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via modulating gut microbiota and the PPARγ/NF-κB pathway |
| Diosmetin | 📋 | | | | 37074600 | Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function |
| Essential Fatty Acids | 📋 | ✍ | | | 36364928 | Essential Fatty Acid Deficiency in Cystic Fibrosis Disease Progression: Role of Genotype and Sex |
| Eucommia | 📋 | ✍ | ⛔ | | 34853273 | Inhibition Effect of Eucommia ulmoides Leaf Extract on Interleukin 8 Production by A549 Cells |
| Eurycomanone | 📋 | | | | 36054770 | Eurycomanol and eurycomanone as potent inducers for cell-cycle arrest and apoptosis in small and large human lung cancer cell lines |
| Flaxseed Oil | 📋 | ✍ | ⛔ | | 35800445 | In Vivo Antitumoral Effects of Linseed Oil and Its Combination With Doxorubicin |
| Garlic Oil | 📋 | | ⛔ | | 38613798 | Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H2S generation |
| Geniposide | 📋 | | | | 36382092 | Geniposide inhibits cell proliferation and migration in human oral squamous carcinoma cells via AMPK and JNK signaling pathways |
| Geraniin | 📋 | | | | 35002405 | Geraniin inhibits cell growth and promoted autophagy-mediated cell death in the nasopharyngeal cancer C666-1 cells |
| Glucosamine | 📋 | ✍ | ⛔ | | 34526168 | Glucosamine use, smoking and risk of incident chronic obstructive pulmonary disease: A large prospective cohort study |
| Glutathione | 📋 | ✍ | ⛔ | | 32856877 | The Protective Effect of Antioxidants in Areca Nut Extract-Induced Oral Carcinogenesis |
| Honeysuckle | 📋 | | ⛔ | | 38115057 | Lonicera japonica Thunb extract ameliorates lipopolysaccharide-induced acute lung injury associated with luteolin-mediated suppression of NF-κB signaling pathway |
| Hypericin | 📋 | | | | 33050761 | Hypericin, a medicinal compound from St. John's Wort, inhibits genotoxicity induced by mutagenic agents in V79 cells |
| Hyssop | 📋 | ✍ | ⛔ | | 35572723 | Exploration of the Molecular Mechanisms of Hyssopus cuspidatus Boriss Treatment of Asthma in an mRNA-miRNA Network via Bioinformatics Analysis |
| Indian Mulberry | 📋 | ✍ | ⛔ | | 38507138 | Ameliorative Effect of Morinda officinalis oligosaccharides on LPS-induced Acute Lung Injury |
| Kudzu Root | 📋 | ✍ | ⛔ | | 36471975 | [Mechanism of Puerariae Lobatae Radix against lung cancer by inhibiting histone demethylase LSD1] |
| L-Methionine | 📋 | ✍ | ⛔ | | 38521369 | L-Methionine accentuates anti-tumor action of Gefitinib in Gefitinib-resistant lung adenocarcinoma: Role of EGFR/ERK/AKT signaling and histone H3K36me2 alteration |
| L-Theanine | 📋 | ✍ | ⛔ | | 27908701 | Inhibitory effects of l-theanine on airway inflammation in ovalbumin-induced allergic asthma |
| L-Tryptophan | 📋 | ✍ | ⛔ | | 32789611 | Tryptophan decreases the intensity of lipopolysaccharide-induced acute lung injury in a rat model |
| Lactobacillus plantarum | 📋 | | ⛔ | | 38553470 | Lactobacillus plantarum L168 improves hyperoxia-induced pulmonary inflammation and hypoalveolarization in a rat model of bronchopulmonary dysplasia |
| Lavender | 📋 | ✍ | ⛔ | | 37663382 | Lavender ( Lavandula angustifolia) syrup as an adjunct to standard care in patients with mild to moderate COVID-19: An open-label, randomized, controlled clinical trial |
| Lupeol | 📋 | | | | 35486494 | Lupeol triggers oxidative stress, ferroptosis, apoptosis and restrains inflammation in nasopharyngeal carcinoma via AMPK/NF-κB pathway |
| Marjoram Essential Oil | 📋 | | ⛔ | | 38068868 | Exploring the Anticancer Potential of Origanum majorana Essential Oil Monoterpenes Alone and in Combination against Non-Small Cell Lung Cancer |
| Morin | 📋 | | | | 34843935 | Morin inhibits the transformation of fibroblasts towards myofibroblasts through regulating "PPAR-γ-glutaminolysis-DEPTOR" pathway in pulmonary fibrosis |
| Nootkatone | 📋 | | | | 37466343 | Nootkatone attenuates airway inflammation in asthmatic mice through repressing ROS-induced NLRP3 inflammasome activation |
| Nuciferine | 📋 | | | | 37833979 | Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway |
| Nutmeg | 📋 | ✍ | ⛔ | | 29468481 | Licarin A induces cell death by activation of autophagy and apoptosis in non-small cell lung cancer cells |
| Omega-9 Fatty Acids | 📋 | | | | 37464819 | Effect of ω-9MUFAs in Fat Emulsion on Serum Interleukin-6 in Rats with Lipopolysaccharide-induced Lung Injury |
| Orange Essential Oil | 📋 | ✍ | ⛔ | | 32837899 | Effects of essential oils on symptoms and course (duration and severity) of viral respiratory infections in humans: A rapid review |
| Oregano | 📋 | ✍ | ⛔ | | 31450579 | Herbal Tea for the Management of Pharyngitis: Inhibition of Streptococcus pyogenes Growth and Biofilm Formation by Herbal Infusions |
| Oregano Essential Oil | 📋 | ✍ | ⛔ | | 29452197 | Essential oils from Origanum vulgare and Salvia officinalis exhibit antibacterial and anti-biofilm activities against Streptococcus pyogenes |
| Papaya | 📋 | ✍ | ⛔ | | 37283020 | Anticancer Effects of Carica papaya L. and Benzyl Isothiocyanate on an Oral Squamous Cell Carcinoma Cell Line: An In Vitro Study |
| PEA | 📋 | ✍ | ⛔ | | 37892528 | The Efficacy of Palmitoylethanolamide (Levagen+) on the Incidence and Symptoms of Upper Respiratory Tract Infection-A Double Blind, Randomised, Placebo-Controlled Trial |
| Peppermint | 📋 | ✍ | ⛔ | | 37342461 | Treatment of the common cold with herbs used in Ayurveda and Jamu: monograph review and the science of ginger, liquorice, turmeric and peppermint |
| Phosphatidylcholine | 📋 | ✍ | ⛔ | | 33406839 | DHA/EPA-Enriched Phosphatidylcholine Suppresses Tumor Growth and Metastasis via Activating Peroxisome Proliferator-Activated Receptor γ in Lewis Lung Cancer Mice |
| Pomegranate Seed extract | 📋 | | ⛔ | | 36762119 | Does pomegranate extract supplementation improve the clinical symptoms of patients with allergic asthma? A double-blind, randomized, placebo-controlled trial |
| Postbiotics | 📋 | | | | 36968114 | A comprehensive review of the application of probiotics and postbiotics in oral health |
| Progesterone | 📋 | ✍ | ⛔ | | 34865992 | Protective effects of progesterone on pulmonary artery smooth muscle cells stimulated with Interleukin 6 via blocking the shuttling and transcriptional function of STAT3 |
| Pumpkin Seed Oil | 📋 | ✍ | ⛔ | | 37147356 | The potential role of pumpkin seeds oil on methotrexate-induced lung toxicity |
| Rhubarb | 📋 | | ⛔ | | 35933455 | Molecular mechanism of Rhubarb in the treatment of non-small cell lung cancer based on network pharmacology and molecular docking technology |
| Sage Essential Oil | 📋 | | ⛔ | | 29452197 | Essential oils from Origanum vulgare and Salvia officinalis exhibit antibacterial and anti-biofilm activities against Streptococcus pyogenes |
| SAMe | 📋 | ✍ | ⛔ | | 37880804 | SAM protects against alveolar septal cell apoptosis in autoimmune emphysema rats |
| Serrapeptase | 📋 | ✍ | ⛔ | | 33353415 | Amelioration of Bleomycin and Methotrexate-Induced Pulmonary Toxicity by Serratiopeptidase and Fisetin |
| Sesame Oil | 📋 | | ⛔ | | 34824517 | Novel Treatment Approach of Oral Submucous Fibrosis in a 6-year-old Girl: A Case Report |
| Shilajit | 📋 | ✍ | ⛔ | | 20532096 | Shilajit: A panacea for high-altitude problems |
| Sirtuin Activators | 📋 | | | | 36117172 | Roles of sirtuins in asthma |
| Soy Isoflavones | 📋 | ✍ | ⛔ | | 36820212 | Soy isoflavone reduces LPS-induced acute lung injury via increasing aquaporin 1 and aquaporin 5 in rats |
| Spearmint Essential Oil | 📋 | ✍ | ⛔ | | 18705008 | [Effect of Spearmint oil on inflammation, oxidative alteration and Nrf2 expression in lung tissue of COPD rats] |
| Spermidine | 📋 | | | | 38552292 | Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling |
| Strawberry | 📋 | ✍ | ⛔ | | 22328465 | Inhibition of lung tumor development by berry extracts in mice exposed to cigarette smoke |
| Syringic Acid | 📋 | | | | 38692075 | Syringic acid attenuates acute lung injury by modulating macrophage polarization in LPS-induced mice |
| Telmisartan | 📋 | | ⛔ | | 35485217 | Telmisartan ameliorates LPS-induced pneumonia in rats through regulation of the PPARγ/NF-κB pathway |
| Ursolic Acid | 📋 | ✍ | ⛔ | | 37089712 | Inhibitory Effect and Mechanism of Ursolic Acid on Cisplatin-Induced Resistance and Stemness in Human Lung Cancer A549 Cells |
| Vegetables | 📋 | | | | 35956264 | The Effects of Increasing Fruit and Vegetable Intake in Children with Asthma on the Modulation of Innate Immune Responses |
| Vitamin B1 | 📋 | ✍ | ⛔ | | 35814219 | Thiamine May Be Beneficial for Patients With Ventilator-Associated Pneumonia in the Intensive Care Unit: A Retrospective Study Based on the MIMIC-IV Database |
| Vitamin B3 | 📋 | ✍ | ⛔ | | 38311664 | Association of dietary niacin intake with the prevalence and incidence of chronic obstructive pulmonary disease |
| Vitamin K2 mk-7 | 📋 | ✍ | | | 38534726 | Protective Effect of Vitamin K2 (MK-7) on Acute Lung Injury Induced by Lipopolysaccharide in Mice |
| White Tea | 📋 | | ⛔ | | 31163217 | White tea - A cost effective alternative to EGCG in fight against benzo(a)pyrene (BaP) induced lung toxicity in SD rats |
| Yam | 📋 | | | | 36105471 | A sesquiterpene isolated from the stems and leaves of Dioscorea opposita thunb. Transforms the composition of immune cells through ER β in a mouse model of LPS-induced lung injury |
| Yogurt | 📋 | | ⛔ | | 38577161 | Dairy intake in association with asthma symptoms among a large sample of children and adolescents: a cross-sectional study |
| Zeaxanthin | 📋 | ✍ | ⛔ | | 38457968 | Association between carotenoids and the prevalence of chronic obstructive pulmonary disease in the United States |
| 5-HTP | 📋 | ✍ | ⛔ | | 22842218 | Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan |
| Acetyl-L-Carnitine | 📋 | ✍ | ⛔ | | 21542052 | Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis |
| Activated Charcoal | 📋 | ✍ | ⛔ | | 36582570 | The Utilization of Activated Charcoal in the Management of Anaphylaxis: A Case Series |
| Alpha-Linolenic Acid | 📋 | ✍ | ⛔ | | 38068849 | Protective Effect of Alpha-Linolenic Acid on Human Oral Squamous Cell Carcinoma Metastasis and Apoptotic Cell Death |
| Apricot | 📋 | | ⛔ | | 31550185 | Trans-Himalayan Phytococktail Confers Protection Against Hypobaric Hypoxia-Induced Hippocampal Neurodegeneration and Memory Impairment in Male Sprague Dawley Rats |
| Argan Oil | 📋 | ✍ | ⛔ | | 22465906 | Antithrombotic activity of argan oil: an in vivo experimental study |
| Bacopa Monnieri | 📋 | ✍ | ⛔ | | 37951147 | Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma |
| Bee Pollen | 📋 | ✍ | ⛔ | | 31274310 | Bee Pollen Extracts Modulate Serum Metabolism in Lipopolysaccharide-Induced Acute Lung Injury Mice with Anti-Inflammatory Effects |
| Beer | 📋 | | | | 37280663 | Chemo-preventive effects and antitumorigenic mechanisms of beer and nonalcoholic beer toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) - induced lung tumorigenesis in A/J mice |
| Bergamottin | 📋 | | | | 34812690 | Bergamottin alleviates LPS-induced acute lung injury by inducing SIRT1 and suppressing NF-κB |
| Bilobalide | 📋 | | | | 36733844 | Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide |
| Bitter Orange | 📋 | ✍ | ⛔ | | 36726839 | The Effect of Citrus aurantium on Non-Small-Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology |
| Boric Acid | 📋 | ✍ | ⛔ | | 35007916 | Anti-cancer effect of boron derivatives on small-cell lung cancer |
| Buckwheat | 📋 | | ⛔ | | 23019909 | [Protection and mechanism of Fagopyrum cymosum on lung injury in rats with Klebsiella pneumonia] |
| Calcium | 📋 | ✍ | ⛔ | | 36364831 | Investigating Causal Associations of Circulating Micronutrients Concentrations with the Risk of Lung Cancer: A Mendelian Randomization Study |
| Capsanthin | 📋 | | | | 36141454 | The Utility of Capsicum annuum L. in Internal Medicine and In Dentistry: A Comprehensive Review |
| Cardamom | 📋 | ✍ | ⛔ | | 34968666 | Black cardamom (Amomum subulatum Roxb.) fruit extracts exhibit apoptotic activity against lung cancer cells |
| Carrot | 📋 | | ⛔ | | 31552816 | Is carrot consumption associated with a decreased risk of lung cancer? A meta-analysis of observational studies |
| Chaga Mushrooms | 📋 | ✍ | ⛔ | | 38720012 | Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism |
| Chamomile Essential Oil | 📋 | ✍ | ⛔ | | 34459765 | Dina V. Shorikova, Eugene I. Shorikov THE EXPERIENCE OF TREATMENT THE PATIENTS WITH COMPLICATED VIRAL RESPIRATORY TRACT INFECTIONS: ROLE OF HIGH-CONCENTRATED OXYGEN INHALATIONS ADDING CAMOMILE OIL |
| Cheese | 📋 | | ⛔ | | 38577161 | Dairy intake in association with asthma symptoms among a large sample of children and adolescents: a cross-sectional study |
| Chicory | 📋 | ✍ | ⛔ | | 38045213 | Cichorium intybus L. significantly alleviates cigarette smoke-induced acute lung injury by lowering NF-κB pathway activation and inflammatory mediators |
| Chondroitin | 📋 | ✍ | ⛔ | | 34176780 | Chondroitin sulfate in tissue remodeling: Therapeutic implications for pulmonary fibrosis |
| Citral | 📋 | | | | 29568932 | Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents |
| Citronella Essential Oil | 📋 | ✍ | ⛔ | | 34065064 | Cymbopogon winterianus Essential Oil Attenuates Bleomycin-Induced Pulmonary Fibrosis in a Murine Model |
| Copper | 📋 | ✍ | ⛔ | | 36185249 | A pro-oxidant combination of resveratrol and copper down-regulates hallmarks of cancer and immune checkpoints in patients with advanced oral cancer: Results of an exploratory study (RESCU 004) |
| Coriander | 📋 | | ⛔ | | 31747377 | Vietnamese coriander inhibits cell proliferation, survival and migration via suppression of Akt/mTOR pathway in oral squamous cell carcinoma |
| Corn Silk | 📋 | ✍ | ⛔ | | 38367774 | Activities of polysaccharide fractions from corn silk: Hemostatic, immune, and anti-lung cancer potentials |
| Cornus | 📋 | | | | 36086972 | Cornus iridoid glycoside alleviates sepsis-induced acute lung injury by regulating NF-κB and Nrf2/HO-1 pathways |
| Costus | 📋 | ✍ | ⛔ | | 37259460 | Protective Potential of Saussurea costus (Falc.) Lipsch. Roots against Cyclophosphamide-Induced Pulmonary Injury in Rats and Its In Vitro Antiviral Effect |
| Crocetin | 📋 | | | | 26646898 | Crocetin Activates Foxp3 Through TIPE2 in Asthma-Associated Treg Cells |
| Cyanidin | 📋 | ✍ | | | 33760143 | Cyanidin‑3‑O‑β‑glucoside protects against pulmonary artery hypertension induced by monocrotaline via the TGF‑β1/p38 MAPK/CREB signaling pathway |
| D-Mannose | 📋 | ✍ | ⛔ | | 37845392 | D-mannose induces TFE3-dependent lysosomal degradation of EGFR and inhibits the progression of NSCLC |
| D-Ribose | 📋 | ✍ | ⛔ | | 17604325 | Preservation of diastolic function in monocrotaline-induced right ventricular hypertrophy in rats |
| Dairy | 📋 | | | | 37650016 | Influence of dairy products consumption on oral cancer risk: A meta-analysis |
| Date | 📋 | | ⛔ | | 35233390 | Cytotoxic and Antioxidant Effects of Phoenix dactylifera L. (Ajwa Date Extract) on Oral Squamous Cell Carcinoma Cell Line |
| DIM | 📋 | ✍ | ⛔ | | 35847018 | Curcumin, thymoquinone, and 3, 3'-diindolylmethane combinations attenuate lung and liver cancers progression |
| Eclipta Alba | 📋 | ✍ | | | 37487966 | A methanolic extract of Eclipta prostrata (L.) L. decreases inflammation in a murine model of chronic allergic asthma via inhibition of the NF-kappa-B pathway |
| Equol | 📋 | ✍ | ⛔ | | 35435186 | [Equol and its enantiomers inhibited urethane-induced lung cancer in mice] |
| Frankincense Essential Oil | 📋 | | ⛔ | | 35807419 | Effects of Frankincense Compounds on Infection, Inflammation, and Oral Health |
| Galangal | 📋 | ✍ | ⛔ | | 30187896 | Volatile oil from alpinia officinarum promotes lung cancer regression in vitro and in vivo |
| Genipin | 📋 | | | | 37792550 | Apoptotic activity of genipin in human oral squamous cell carcinoma in vitro by regulating STAT3 signaling |
| Giloy | 📋 | ✍ | ⛔ | | 35848691 | Pro-apoptotic, anti-metastatic, and anti-telomerase activity of Tinospora cordifolia and its active polysaccharide arabinogalactan during Benzo(a)pyrene-induced lung carcinogenesis |
| Grape | 📋 | | ⛔ | | 34283318 | Do grape and black mulberry molasses have an effect on oral mucositis and quality of life in patients with head and neck cancer? |
| Grapefruit | 📋 | | ⛔ | | 33752061 | Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway |
| Guggul | 📋 | ✍ | ⛔ | | 37196815 | Protective effect of oleo-gum resin of Commiphora wightii against elastase-induced chronic obstructive pulmonary disease-linked lung inflammation and emphysema: Isolation and identification of key bioactive phytoconstituent |
| Gymnema Sylvestre | 📋 | ✍ | ⛔ | | 36662401 | Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-κB/MAPK pathway |
| Hawthorn | 📋 | ✍ | ⛔ | | 33112559 | Anti-Oxidant, Anti-Hemolytic Effects of Crataegus aronia Leaves and Its Anti- Proliferative Effect Enhance Cisplatin Cytotoxicity in A549 Human Lung Cancer Cell Line |
| Hops | 📋 | ✍ | ⛔ | | 35229981 | Xanthohumol targets the JNK1/2 signaling pathway in apoptosis of human nasopharyngeal carcinoma cells |
| Horny Goat Weed | 📋 | ✍ | ⛔ | | 31807551 | Wenshen decoction suppresses inflammation in IL-33-induced asthma murine model via inhibiting ILC2 activation |
| Horse Chestnut | 📋 | ✍ | ⛔ | | 30711418 | Aesculus hippocastanum L. seed extract shows virucidal and antiviral activities against respiratory syncytial virus (RSV) and reduces lung inflammation in vivo |
| Iron | 📋 | ✍ | ⛔ | | 33002395 | Oral Manifestations of Nutritional Deficiencies: Single Centre Analysis |
| Isoquercitrin | 📋 | | | | 37712196 | Isoquercitrin promotes ferroptosis and oxidative stress in nasopharyngeal carcinoma via the AMPK/NF-κB pathway |
| Kacip Fatimah | 📋 | ✍ | ⛔ | | 38398785 | Cytotoxic Effects of Ardisiacrispin A from Labisia pumila on A549 Human Lung Cancer Cells |
| Kimchi | 📋 | | ⛔ | | 37110390 | Protective Effect of Novel Lactobacillus plantarum KC3 Isolated from Fermented Kimchi on Gut and Respiratory Disorders |
| Krill Oil | 📋 | ✍ | ⛔ | | 33398741 | Krill oil and low-dose aspirin combination mitigates experimentally induced silicosis in rats: role of NF-κB/TGF-β1/MMP-9 pathway |
| L-Histidine | 📋 | ✍ | ⛔ | | 34125142 | Histidine ameliorates elastase- and lipopolysaccharide-induced lung inflammation by inhibiting the activation of the NLRP3 inflammasome |
| L-Proline | 📋 | ✍ | ⛔ | | 35910374 | Exogenous proline enhances susceptibility of NSCLC to cisplatin via metabolic reprogramming and PLK1-mediated cell cycle arrest |
| Lecithin | 📋 | ✍ | ⛔ | | 33009655 | A dry powder inhalable formulation of salvianolic acids for the treatment of pulmonary fibrosis: safety, lung deposition, and pharmacokinetic study |
| Lemon | 📋 | | ⛔ | | 33512251 | Effect of Honey-Lemon Spray Versus Benzydamine Hydrochloride Spray on Radiation-Induced Acute Oral Mucositis in Head and Neck Cancer Patients: A Pilot, Randomized, Double-Blind, Active-Controlled Clinical Trial |
| Lemon Balm | 📋 | ✍ | ⛔ | | 29790547 | Melissa officinalis L. ethanolic extract inhibits the growth of a lung cancer cell line by interfering with the cell cycle and inducing apoptosis |
| Lemon Balm Essential Oil | 📋 | ✍ | ⛔ | | 32041100 | Methylcellulose Hydrogel with Melissa officinalis Essential Oil as a Potential Treatment for Oral Candidiasis |
| Lemon Essential Oil | 📋 | ✍ | ⛔ | | 32837899 | Effects of essential oils on symptoms and course (duration and severity) of viral respiratory infections in humans: A rapid review |
| Limonin | 📋 | | | | 37481848 | Limonin, a novel AMPK activator, protects against LPS-induced acute lung injury |
| Lingonberry | 📋 | | ⛔ | | 34835994 | Lingonberries-General and Oral Effects on the Microbiome and Inflammation |
| Long Pepper | 📋 | | ⛔ | | 25630105 | Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats |
| Madecassoside | 📋 | | | | 32581788 | Madecassoside Protects Against LPS-Induced Acute Lung Injury via Inhibiting TLR4/NF-κB Activation and Blood-Air Barrier Permeability |
| Malva Sylvestris | 📋 | | ⛔ | | 30984577 | Short-course administration of a traditional herbal mixture ameliorates asthma symptoms of the common cold in children |
| Malvidin | 📋 | | | | 28974439 | Blueberry and Malvidin Inhibit Cell Cycle Progression and Induce Mitochondrial-Mediated Apoptosis by Abrogating the JAK/STAT-3 Signalling Pathway |
| Mandarin | 📋 | | | | 35809307 | Network pharmacology study of Citrus reticulata and Pinellia ternata in the treatment of non-small cell lung cancer |
| Mandarin Essential Oil | 📋 | | ⛔ | | 37981111 | Inhalation of Citrus Reticulata essential oil alleviates airway inflammation and emphysema in COPD rats through regulation of macrophages |
| Mango | 📋 | | ⛔ | | 38196561 | Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells |
| Marigold | 📋 | ✍ | ⛔ | | 32331341 | Clinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study |
| Marshmallow Root | 📋 | | ⛔ | | 30984577 | Short-course administration of a traditional herbal mixture ameliorates asthma symptoms of the common cold in children |
| Milk | 📋 | | ⛔ | | 34978666 | Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis |
| Modified Citrus Pectin | 📋 | ✍ | ⛔ | | 25794149 | Heat-modified citrus pectin induces apoptosis-like cell death and autophagy in HepG2 and A549 cancer cells |
| MUFA | 📋 | | ⛔ | | 37464819 | Effect of ω-9MUFAs in Fat Emulsion on Serum Interleukin-6 in Rats with Lipopolysaccharide-induced Lung Injury |
| Mugwort | 📋 | | ⛔ | | 37110139 | Ethanolic Extract of Artemisia vulgaris Leaf Promotes Apoptotic Cell Death in Non-Small-Cell Lung Carcinoma A549 Cells through Inhibition of the Wnt Signaling Pathway |
| Mushrooms | 📋 | | ⛔ | | 35440880 | Immunomodulatory Effect and an Intervention of TNF Signalling Leading to Apoptotic and Cell Cycle Arrest on ORL-204 Oral Cancer Cells by Tiger Milk Mushroom, Lignosus rhinocerus |
| Mustard | 📋 | | ⛔ | | 35899230 | Do Chest Compresses with Mustard or Ginger Affect Warmth Regulation in Healthy Adults? A Randomized Controlled Trial |
| Myrrh | 📋 | ✍ | ⛔ | | 29747538 | Protective effect of standardized extract of Myrtus communis L. (myrtle) on experimentally bleomycin-induced pulmonary fibrosis: biochemical and histopathological study |
| Myrtle | 📋 | ✍ | ⛔ | | 32641957 | Anti-Inflammatory and Anti-Oxidative Effects of Myrtenol in the Rats with Allergic Asthma |
| Nicotinamide Riboside | 📋 | ✍ | ⛔ | | 36052583 | [Study on the Protective effect and mechanism of Nicotinamide Riboside on lung injury in paraquat intoxicated mice] |
| Nitrate | 📋 | ✍ | ⛔ | | 38733290 | Effects of dietary nitrate supplementation on oral health and associated markers of systemic health: a systematic review |
| Noni | 📋 | | ⛔ | | 31807551 | Wenshen decoction suppresses inflammation in IL-33-induced asthma murine model via inhibiting ILC2 activation |
| Nuts | 📋 | | ⛔ | | 35920657 | Association between nut consumption and cancer risk: a meta-analysis |
| Oleanolic Acid | 📋 | | | | 37021507 | Oleanolic Acid Acetate Inhibits Mast Cell Activation in Ovalbumin-Induced Allergic Airway Inflammation |
| Oleic Acid | 📋 | | ⛔ | | 33957086 | Oleic acid and oleoylethanolamide decrease interferon-γ-induced expression of PD-L1 and induce apoptosis in human lung carcinoma cells |
| Orange | 📋 | | ⛔ | | 19065586 | Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis |
| Osmanthus | 📋 | ✍ | ⛔ | | 24386002 | The Ethanol Extract of Osmanthus fragrans Flowers Reduces Oxidative Stress and Allergic Airway Inflammation in an Animal Model |
| Papain | 📋 | ✍ | ⛔ | | 21356017 | Stain removal efficacy of a novel dentifrice containing papain and Bromelain extracts--an in vitro study |
| Pear | 📋 | | ⛔ | | 15253858 | Asian pear pectin administration during presensitization inhibits allergic response to ovalbumin in BALB/c mice |
| Pectin | 📋 | ✍ | ⛔ | | 33772084 | High-fiber diets attenuate emphysema development via modulation of gut microbiota and metabolism |
| Persimmon | 📋 | | ⛔ | | 32835798 | Polysaccharide isolated from persimmon leaves (Diospyros kaki Thunb.) suppresses TGF-β1-induced epithelial-to-mesenchymal transition in A549 cells |
| Pine Needle Essential Oil | 📋 | ✍ | ⛔ | | 35744988 | Pinus sylvestris L. and Syzygium aromaticum (L.) Merr. & L. M. Perry Essential Oils Inhibit Endotoxin-Induced Airway Hyperreactivity despite Aggravated Inflammatory Mechanisms in Mice |
| Pineapple | 📋 | ✍ | ⛔ | | 27181342 | Use of honey associated with Ananas comosus (Bromelin) in the treatment of acute irritative cough |
| Plum | 📋 | | ⛔ | | 33641052 | New Insights into the Mechanisms of Polyphenol from Plum Fruit Inducing Apoptosis in Human Lung Cancer A549 Cells Via PI3K/AKT/FOXO1 Pathway |
| Polypodium Leucotomos | 📋 | ✍ | ⛔ | | 23093910 | Polypodium leucotomos Extract use to prevent and reduce the risk of infectious diseases in high performance athletes |
| Poria Mushrooms | 📋 | ✍ | | | 33919400 | Poria cocos Modulates Th1/Th2 Response and Attenuates Airway Inflammation in an Ovalbumin-Sensitized Mouse Allergic Asthma Model |
| Prickly Pear | 📋 | | ⛔ | | 35214853 | Opuntia ficus-indica Alleviates Particulate Matter 10 Plus Diesel Exhaust Particles (PM10D)-Induced Airway Inflammation by Suppressing the Expression of Inflammatory Cytokines and Chemokines |
| Radish | 📋 | | ⛔ | | 38336182 | Novel insights into the anti-asthmatic effect of Raphanus sativus L. (Raphani Semen): Targeting immune cells, inflammatory pathways and oxidative stress markers |
| Red Yeast Rice | 📋 | ✍ | ⛔ | | 35571660 | Inhibitory effect of lovastatin on human lung cancer cell proliferation by regulating the ERK1/2 and COX-2 pathways |
| Shiitake Mushrooms | 📋 | ✍ | ⛔ | | 36364151 | Lentinus edodes Polysaccharides Alleviate Acute Lung Injury by Inhibiting Oxidative Stress and Inflammation |
| Soy | 📋 | ✍ | ⛔ | | 35913505 | Isoflavone and soy food intake and risk of lung cancer in never smokers: report from prospective studies in Japan and China |
| Star Fuit | 📋 | | ⛔ | | 33613291 | Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evaluation |
| Tea Tree Essential Oil | 📋 | | ⛔ | | 32578760 | Antibiofilm Efficacy of Tea Tree Oil and of Its Main Component terpinen-4-ol Against Candida Albicans |
| Terpenoids | 📋 | | | | 36034851 | Efficacy of terpenoids in attenuating pulmonary edema in acute lung injury: A meta-analysis of animal studies |
| Tongkat Ali | 📋 | ✍ | ⛔ | | 32945500 | Inactivation of AKT/NF‑κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin |
| Trans-Resveratrol | 📋 | | | | 33336760 | The potential role of trans-resveratrol/carboxymethylated (1.3/1.6)-β-d-glucan minimizing symptoms and improve healing after functional endoscopic sinus surgery |
| Trehalose | 📋 | | ⛔ | | 33466366 | Macrophage Autophagy and Silicosis: Current Perspective and Latest Insights |
| Turnip | 📋 | | ⛔ | | 34523644 | The petroleum ether extract of Brassica rapa L. induces apoptosis of lung adenocarcinoma cells via the mitochondria-dependent pathway |
| Vitamin B Complex | 📋 | | ⛔ | | 36282901 | Vitamin B complex blocks the dust fall PM2 .5 -induced acute lung injury through DNA methylation in rats |
| Vitamin B12 | 📋 | ✍ | ⛔ | | 19277125 | Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial |
| Vitamin B2 | 📋 | ✍ | ⛔ | | 36625571 | Riboflavin Targets the Cellular Metabolic and Ribosomal Pathways of Candida albicans In Vitro and Exhibits Efficacy against Oropharyngeal Candidiasis |
| Vitamin B5 | 📋 | ✍ | ⛔ | | 29176546 | Pantethine Down-Regulates Leukocyte Recruitment and Inflammatory Parameters in a Mouse Model of Allergic Airway Inflammation |
| Vitamin K1 | 📋 | ✍ | ⛔ | | 18511355 | Efficacy of High Dose Phylloquinone in Correcting Vitamin K Deficiency in Cystic Fibrosis |
| Vitamin K2 | 📋 | ✍ | ⛔ | | 30813635 | Mechanisms of PKC-Mediated Enhancement of HIF-1α Activity and Its Inhibition by Vitamin K2 in Hepatocellular Carcinoma Cells |
| Vitex | 📋 | ✍ | ⛔ | | 32972249 | Essential Oils from Vitex agnus castus L. Leaves Induces Caspase-Dependent Apoptosis of Human Multidrug-Resistant Lung Carcinoma Cells through Intrinsic and Extrinsic Pathways |
| Watercress | 📋 | ✍ | ⛔ | | 37057243 | Effect of Nasturtium Extract on Oral Cancer |
| Whey Protein | 📋 | ✍ | ⛔ | | 38135472 | Effects of whey protein complex combined with low-intensity exercise in elderly inpatients with COPD at a stable stage |
| Wine | 📋 | | ⛔ | | 35080021 | Alcohol intake, beverage type, and lung function: a multicohort study of Chinese adults |
| Withanolides | 📋 | | | | 33530424 | Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers |
| Xylitol | 📋 | ✍ | ⛔ | | 35631164 | Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer |
| Yohimbine | 📋 | ✍ | | | 35970968 | Anticancer potential of yohimbine in drug-resistant oral cancer KB-ChR-8-5 cells |
